Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067744 | 1.00 | KDM4E (0.36) | KDM4EHSD17B10HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4071056 | 1.00 | KDM4E (0.36) | KDM4EHSD17B10HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4063303 | 0.89 | KDM4E (0.34) | KDM4EHSD17B10HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4063309 | 0.89 | KDM4E (0.34) | KDM4EHSD17B10HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4067972 | 0.88 | HSD17B10 (0.33) | KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL4067977 | 0.88 | HSD17B10 (0.33) | KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL4066121 | 0.86 | HTR4 (0.37) | — | |
| SCHEMBL4066124 | 0.86 | HTR4 (0.37) | — | |
| SCHEMBL4062239 | 0.85 | DHODH (0.43) | KDM4EHSD17B10HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4062237 | 0.85 | DHODH (0.43) | KDM4EHSD17B10HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041153-B1 | NEW 5-THIOXYLOPYRANOSE DERIVATIVES | FOURNIER LAB SA (FR) | 2009-10-21 | — | — | EP | disclosed |