Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4069529 | 0.81 | KDM4E (0.50) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL9853966 | 0.78 | TAAR1 (0.61) | RAB9ATAAR1KDM4ESMN1; SMN2 | |
| SCHEMBL1675377 | 0.78 | TTR (0.68) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL1675479 | 0.77 | NPC1 (0.64) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL1675639 | 0.75 | TTR (0.56) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL1675383 | 0.75 | TBXAS1 (0.56) | — | |
| SCHEMBL1675545 | 0.74 | MAOA (0.55) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL10531244 | 0.74 | TAAR1 (0.50) | TAAR1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1675466 | 0.73 | HPSE (0.64) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL7290750 | 0.73 | TAAR1 (0.43) | NPC1RAB9ATAAR1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151546-A2 | METHODS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |