SCHEMBL406259

SCHEMBL406259

F[C](C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1270561 0.90 THRB (0.43) THRB
SCHEMBL19548410 0.88 THRB (0.48) THRB
SCHEMBL19548466 0.88 THRB (0.48) THRB
SCHEMBL21462653 0.88 THRB (0.48) THRB
SCHEMBL10435824 0.88 THRB (0.48) THRB
SCHEMBL10435806 0.88 THRB (0.48) THRB
SCHEMBL18242667 0.88 THRB (0.48) THRB
SCHEMBL9820622 0.88 THRB (0.48) THRB
SCHEMBL6230891 0.86 THRB (0.36) THRB
SCHEMBL19920967 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003187-B Polyfluoroalkyl substituted benzofuran compound and preparation method thereof 南京工业大学 2021-11-05 CN claimed
CN-110003187-A Polyfluoroalkyl substituted benzofuran compound and preparation method thereof 南京工业大学 2019-07-12 CN claimed
EP-0764628-B1 Diesters of pyrocarbonic acid, their preparation and their use CIBA SC HOLDING AG (CH) 2001-03-14 EP claimed
CN-115124700-B Polyarylate resin and electrophotographic photoreceptor 京瓷办公信息系统株式会社 2024-07-09 CN disclosed
US-20240201607-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2024-06-20 US disclosed
US-20240192614-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2024-06-13 US disclosed
US-20240192613-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2024-06-13 US disclosed
EP-4379468-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA Document Solutions Inc. (JP) 2024-06-05 EP disclosed
CN-118092096-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2024-05-28 CN disclosed
CN-118092097-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2024-05-28 CN disclosed
EP-4354226-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY KYOCERA Document Solutions Inc. (JP) 2024-04-17 EP disclosed
US-20090124796-A1 Nucleobase Having Perfluoroalkyl Group and Process for Producing the Same TOSOH CORPORATION (JP) 2009-05-14 US disclosed
EP-2036899-A1 METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER Wako Pure Chemical Industries, Ltd. (JP) 2009-03-18 EP disclosed
CN-101304977-A Nucleic acid base having perfluoroalkyl group and method for producing the same TOSOH CORP (JP) 2008-11-12 CN disclosed
EP-1947092-A1 NUCLEIC ACID BASE HAVING PERFLUOROALKYL GROUP AND METHOD FOR PRODUCING THE SAME Tosoh Corporation (JP) 2008-07-23 EP disclosed
US-20060063944-A1 Estrone derivatives and process for producing same CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2006-03-23 US disclosed
EP-0764628-B1 Diesters of pyrocarbonic acid, their preparation and their use CIBA SC HOLDING AG (CH) 2001-03-14 EP disclosed
EP-0787711-B1 Process for the preparation of alpha,beta-unsaturated carboxylic acids HOFFMANN LA ROCHE (CH) 2000-04-26 EP disclosed
US-5910606-A INTERMEDIATES FOR MAKING PHARMACOLAGICALLY USABLE PRODUCTS AND PESTICIDES HOFFMANN-LA ROCHE INC. (US) 1999-06-08 US disclosed
EP-0787711-A2 Process for the preparation of alpha,beta-unsaturated carboxylic acids F. HOFFMANN-LA ROCHE AG (CH) 1997-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063944-A1 Estrone derivatives and process for producing same HSD17B11, ESRRA, CYP19A1 THRB 504/4885
US-20090124796-A1 Nucleobase Having Perfluoroalkyl Group and Process for Producing the Same PFAS, FPGS, NUDT1 THRB 2374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.