Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468572 | 0.79 | LMNA (0.62) | KDM4EALDH1A1ARFEN1KDR | |
| SCHEMBL1771631 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1ARKDM5ABRD4 | |
| SCHEMBL16652203 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1ARGLAGAA | |
| SCHEMBL31081977 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1ARDAOGLA | |
| SCHEMBL2054683 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1ARKDRKDM5A | |
| SCHEMBL2272868 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1ARDAOGLA | |
| SCHEMBL28834693 | 0.78 | KDR (0.51) | KDM4EALDH1A1ARFEN1KDR | |
| SCHEMBL3223994 | 0.78 | LMNA (0.66) | KDM4EALDH1A1ARDAOGAA | |
| SCHEMBL8363345 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1FEN1KDRGLA | |
| SCHEMBL26341078 | 0.76 | MAP2 (0.50) | KDM4EALDH1A1FEN1KDRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032177-A1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS I AND II | IDENIX PHARMACEUTICALS, INC. (US) | 2009-03-12 | — | — | WO | disclosed |
| CN-1535151-A | Novel anti-infectives | ʷ��˿�������ȳ�ķ����˾ | 2004-10-06 | — | — | CN | disclosed |