Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468572 | 0.79 | LMNA (0.62) | KDRKDM4EALDH1A1GLAGAA | |
| SCHEMBL5453934 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL4062622 | 0.78 | KDM4E (0.59) | KDRKDM4EALDH1A1GLAGAA | |
| SCHEMBL26341078 | 0.76 | MAP2 (0.50) | KDRKDM4EALDH1A1GLAGAA | |
| SCHEMBL1771152 | 0.75 | AR (0.69) | AR | |
| SCHEMBL29507335 | 0.75 | CYP1A2 (0.62) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL450729 | 0.75 | CYP1A2 (0.62) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL2056416 | 0.74 | KDM4E (0.45) | KDM4EALDH1A1ARHPGDLMNA | |
| SCHEMBL29612308 | 0.74 | HPGD (0.67) | KDRKDM4EALDH1A1GLAGAA | |
| SCHEMBL2054651 | 0.74 | KIF11 (0.51) | KDM4EALDH1A1GLAGAAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105899510-A | Substituted imidazo[1,2-a]pyrazinecarboxamides and use thereof | 拜耳制药股份公司 | 2016-08-24 | — | — | CN | disclosed |