Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157444 | 0.88 | MAPK1 (0.65) | HTTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL10945970 | 0.88 | ALDH1A1 (0.49) | HTTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL27903906 | 0.87 | HTT (0.56) | HTTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL536179 | 0.86 | HTT (0.62) | HTTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL4062441 | 0.85 | PARP1 (0.54) | HTTKDM4EHPGDALDH1A1TUBB4A | |
| SCHEMBL7428124 | 0.85 | CTSD (0.46) | HTTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9634001 | 0.84 | HTT (0.61) | HTTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL152563 | 0.84 | MAPT (0.59) | HTTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL29603325 | 0.84 | MAPT (0.59) | HTTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL32674573 | 0.83 | MYC (0.57) | HTTKDM4EHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |