Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776927 | 0.92 | CNR2 (0.45) | CTSDALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL7430967 | 0.86 | CTSD (0.51) | CTSDALDH1A1HPGDCLCN2HTT | |
| SCHEMBL4063170 | 0.85 | HTT (0.56) | ALDH1A1HPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL31074983 | 0.84 | NPC1 (0.53) | CTSDALDH1A1HPGDHTTKDM4E | |
| SCHEMBL341330 | 0.84 | NPC1 (0.53) | CTSDALDH1A1HPGDHTTKDM4E | |
| SCHEMBL4062441 | 0.84 | PARP1 (0.54) | CTSDALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL699716 | 0.80 | ALDH1A1 (0.45) | CTSDALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL16672818 | 0.79 | TSHR (0.56) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL29392137 | 0.79 | CTSD (0.63) | CTSDALDH1A1HPGDHTTHSD17B10 | |
| SCHEMBL431 | 0.79 | CTSD (0.63) | CTSDALDH1A1HPGDHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183239-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069821-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-11-23 | — | — | WO | disclosed |