Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14195830 | 1.00 | MAOB (0.62) | MAOBALDH1A1THRATHRBERN1 | |
| SCHEMBL13683800 | 0.98 | ALDH1A1 (0.63) | MAOBALDH1A1THRATHRBERN1 | |
| SCHEMBL4059477 | 0.95 | ALDH1A1 (0.67) | MAOBALDH1A1THRATHRBERN1 | |
| SCHEMBL317833 | 0.91 | MAOB (0.52) | MAOBALDH1A1THRATHRBPLA2G4B | |
| SCHEMBL8749655 | 0.91 | MAOB (0.52) | MAOBALDH1A1THRATHRBPLA2G4B | |
| SCHEMBL20892596 | 0.89 | ALDH1A1 (0.67) | MAOBALDH1A1ERN1L3MBTL1TUBB1 | |
| SCHEMBL5106446 | 0.89 | MAOB (0.50) | MAOBALDH1A1THRATHRBNR5A1 | |
| SCHEMBL8702506 | 0.88 | ALDH1A1 (0.61) | MAOBALDH1A1THRATHRBERN1 | |
| SCHEMBL5885093 | 0.88 | TUBB1 (0.59) | MAOBALDH1A1THRATHRBERN1 | |
| SCHEMBL8067102 | 0.87 | ALDH1A1 (0.63) | MAOBALDH1A1ERN1L3MBTL1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845345-B | Aromatic diamine monomer and preparation method thereof | 中国科学院长春应用化学研究所 | 2021-11-09 | — | — | CN | disclosed |
| CN-110791833-B | Polyimide fiber and preparation method thereof | 中国科学院长春应用化学研究所 | 2021-02-05 | — | — | CN | disclosed |
| CN-110845345-A | Aromatic diamine monomer and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-02-28 | — | — | CN | disclosed |
| CN-110791833-A | Polyimide fiber and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-02-14 | — | — | CN | disclosed |
| CN-100577651-C | Lactam compound and medicinal use thereof | AJINOMOTO KK | 2010-01-06 | — | — | CN | disclosed |
| US-7632830-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2009-12-15 | — | — | US | disclosed |
| EP-1346993-B1 | LACTAM COMPOUNDS AND MEDICAL USE THEREOF | AJINOMOTO KK (JP) | 2009-10-21 | — | — | EP | disclosed |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | AJINOMOTO CO., INC. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-7326701-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2008-02-05 | — | — | US | disclosed |
| CN-1911915-A | Lactam compound and medicinal use thereof | AJINOMOTO KK (JP) | 2007-02-14 | — | — | CN | disclosed |
| US-7153850-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-20060189597-A1 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2006-08-24 | — | — | US | disclosed |
| CN-1269818-C | Lactam compounds and pharmaceutical use thereof | AJINOMOTO KK (JP) | 2006-08-16 | — | — | CN | disclosed |
| CN-1487940-A | Lactam compounds and pharmaceutical use thereof | ֮����ʽ���� | 2004-04-07 | — | — | CN | disclosed |
| US-20040048847-A1 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO. INC (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1346993-A1 | LACTAM COMPOUNDS AND MEDICINAL USE THEREOF | Ajinomoto Co., Inc. (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189597-A1 | Lactam compounds and pharmaceutical use thereof | SLC2A4, SLC2A8, SLC2A1 | MAOB 2230/4885ALDH1A1 911/4885THRA 4242/4885 |
| US-20040048847-A1 | Lactam compounds and pharmaceutical use thereof | SLC2A4, SLC2A8, SLC2A1 | MAOB 2230/4885ALDH1A1 911/4885THRA 4242/4885 |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | SLC2A4, SLC2A8, SLC2A1 | MAOB 2230/4885ALDH1A1 911/4885THRA 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.