SCHEMBL317833

SCHEMBL317833

CCCCCCCCCCCCCCCCCCCCCCOc1ccc(C=O)c(OCCCCCCCCCCCCCCCCCCCCCC)c1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.52
ALDH1A1 P00352 1/20 0.47
NR5A1 Q13285 1/20 0.47
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
PLA2G4B P0C869 1/20 0.45
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
PTPN11 Q06124 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749655 1.00 MAOB (0.52) MAOBALDH1A1NR5A1TSHRTP53
SCHEMBL5106446 0.98 MAOB (0.50) MAOBALDH1A1NR5A1TSHRTP53
SCHEMBL4064858 0.95 ALDH1A1 (0.51) MAOBALDH1A1
SCHEMBL4067770 0.92 MDM2 (0.50) MAOBALDH1A1
SCHEMBL14195830 0.91 MAOB (0.62) MAOBALDH1A1NR5A1PLA2G4BTHRA
SCHEMBL4063273 0.91 MAOB (0.62) MAOBALDH1A1NR5A1PLA2G4BTHRA
SCHEMBL8702506 0.91 ALDH1A1 (0.61) MAOBALDH1A1THRATHRB
SCHEMBL17558110 0.91 MAOB (0.46) MAOBALDH1A1PLA2G4B
SCHEMBL17558112 0.91 MAOB (0.46) MAOBALDH1A1PLA2G4B
SCHEMBL19399340 0.89 MAOB (0.45) MAOBPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778621-B1 PEPTIDE SYNTHESIS METHOD JITSUBO CO LTD (JP) 2023-08-23 EP claimed
EP-4673424-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS Regeneron Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
WO-2024182268-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS REGENERON PHARMACEUTICALS, INC. (US) 2024-09-06 WO disclosed
EP-3778621-B1 PEPTIDE SYNTHESIS METHOD JITSUBO CO LTD (JP) 2023-08-23 EP disclosed
CN-113045628-B Application of antibacterial peptide or variant thereof in preparation of antibacterial product 山东大学 2022-06-14 CN disclosed
EP-3778621-A1 PEPTIDE SYNTHESIS METHOD Jitsubo Co., Ltd. (JP) 2021-02-17 EP disclosed
EP-2711370-B1 METHOD FOR PRODUCING OLIGONUCLEOTIDES AJINOMOTO KK (JP) 2018-01-03 EP disclosed
US-9029528-B2 Solution-based method of making oligonucleotides via phosphoramidite coupling AJINOMOTO CO., INC. (JP) 2015-05-12 US disclosed
EP-2711370-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE Ajinomoto Co., Inc. (JP) 2014-03-26 EP disclosed
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2012-11-22 US disclosed
US-8293948-B2 Reagent for organic synthesis and method of organic synthesis reaction with the reagent JITSUBO CO., LTD. (JP) 2012-10-23 US disclosed
US-20120108788-A1 REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT JITSUBO CO., LTD. (JP) 2012-05-03 US disclosed
US-8093435-B2 Reagent for organic synthesis and method of organic synthesis reaction with the reagent JITSUBO CO., LTD. (JP) 2012-01-10 US disclosed
US-20090299103-A1 Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent NATIONAL UNIVERSITY CORPORATION, TOKYO UNIVERSITY (JP) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299103-A1 Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent COASY, OSTC, OGA MAOB 260/4885ALDH1A1 1146/4885NR5A1 2629/4885
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE RNGTT, POLM, RNMT MAOB 2667/4885ALDH1A1 4056/4885NR5A1 2010/4885
US-20120108788-A1 REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT COASY, OSTC, OGA MAOB 260/4885ALDH1A1 1146/4885NR5A1 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.