SCHEMBL40633

SCHEMBL40633

O=Cc1cccc(Br)c1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP2A6 P11509 2/20 0.47
TRIM24 O15164 2/20 0.45
TRIM33 Q9UPN9 2/20 0.45
ERN1 O75460 4/20 0.43
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
PIM1 P11309 2/20 0.40
PIM3 Q86V86 2/20 0.40
HSD11B1 P28845 2/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PIM2 Q9P1W9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1232196 0.87 LMNA (0.58) LMNAKMT2AMEN1THRBBLM
SCHEMBL16050134 0.81 MEN1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL7670755 0.80 HSD11B1 (0.34) CYP2A6HSD11B1
SCHEMBL14876734 0.80 MEN1 (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL29527038 0.79
SCHEMBL95292 0.79
SCHEMBL146118 0.78 ALDH1A1 (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL30600419 0.78 MEN1 (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL9413412 0.78 MEN1 (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL29621617 0.78 ALDH1A1 (0.50) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-113372268-A 4-oxo-6-methoxy-3- (2, 3-dichlorophenyl) methyl-1 (4H) quinolineacetic acid metabolites 宁夏康亚药业股份有限公司 2021-09-10 CN claimed
CN-109400453-A A kind of preparation method of 2,6- dibromo benzaldehyde 河南师范大学 2019-03-01 CN claimed
CN-106083546-A A kind of preparation method of 3,5 dibromo benzaldehydes 上海引盛生物科技有限公司 2016-11-09 CN claimed
CN-104003887-B A kind of preparation method of Bisolvon 江西东抚制药有限公司 2016-11-02 CN claimed
CN-103739502-B A kind of separation and purification technique of ambroxol alkali 浙江浙邦制药有限公司 2016-06-08 CN claimed
CN-105152947-A Preparation method of 2-amino-3,5-dibromobenzaldehyde JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO LTD 2015-12-16 CN claimed
CN-104788326-A Synthesis method of ambroxol hydrochloride JINAN KANGHE MEDICAL TECHNOLOGY CO LTD 2015-07-22 CN claimed
CN-104447366-A Preparation method of high-purity 2-amino-3, 5-dibromobenzaldehyde JIANGXI RONGXING PHARMACEUTICAL CO LTD 2015-03-25 CN claimed
CN-102617359-A Method for preparing bromhexine hydrochloride SHIJIAZHUANG DONGFANG PHARMACEUTICAL CO LTD 2012-08-01 CN claimed
CN-102558184-A Synthesis method of phthalazine derivative UNIV SOUTHWEST 2012-07-11 CN claimed
CN-102262135-A Method for detecting impurities in ambroxol hydrochloride injection and content determination method 2011-11-30 CN claimed
CN-1833054-B Aqueous acidic solution and method for the electrolytic deposition of copper coatings and use of the solution ATOTECH DEUTSCHLAND GMBH 2011-09-07 CN claimed
CN-101865891-A Ambroxol hydrochloride detection method YUNNAN LONGHAI NATURAL PLANT MEDICINE INDUSTRY CO LTD 2010-10-20 CN claimed
WO-2007076835-A1 METHOD FOR PRODUCTION OF $G(A),$G(B)-UNSATURATED CARBOXYLATE DERIVATIVES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2007-07-12 WO claimed
CN-1833054-A Aqueous acidic solution and method for the electrolytic deposition of copper coatings and use of the solution ATOTECH DEUTSCHLAND GMBH (DE) 2006-09-13 CN claimed
CN-1687023-A Boron developer-1-(2,3,4-trihydroxyl-4,5-dibromo-benzene methyleneneamido)-8-hydroxy naphthalene-3,6-disulfonic acid and preparation method UNIV JIANGNAN (CN) 2005-10-26 CN claimed
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP claimed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO claimed