Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066997 | 0.76 | HTT (0.54) | ALDH1A1KDM4EHTTPOLBKMT2A | |
| SCHEMBL4066957 | 0.69 | HTT (0.56) | ALDH1A1KDM4EHTTHSD17B10POLB | |
| SCHEMBL27835949 | 0.67 | ALDH1A1 (0.55) | ALDH1A1KDM4EHTTHSD17B10POLB | |
| SCHEMBL4070310 | 0.67 | HTT (0.61) | ALDH1A1HTTPOLBLMNAMAPT | |
| SCHEMBL4244216 | 0.66 | MAPT (0.60) | ALDH1A1KDM4EHTTPOLBLMNA | |
| SCHEMBL1077415 | 0.62 | ALDH1A1 (0.50) | ALDH1A1KDM4EHTTHSD17B10POLB | |
| SCHEMBL15426087 | 0.62 | ALDH1A1 (0.70) | ALDH1A1KDM4EHTTHSD17B10KMT2A | |
| SCHEMBL4066328 | 0.62 | HTT (0.56) | ALDH1A1KDM4EHTTHSD17B10POLB | |
| SCHEMBL11340384 | 0.61 | ALDH1A1 (0.57) | ALDH1A1KDM4EHTTHSD17B10POLB | |
| SCHEMBL12670811 | 0.59 | RORC (0.57) | ALDH1A1KDM4EHTTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |