Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068393 | 0.92 | CYP19A1 (0.49) | CYP19A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13848375 | 0.87 | MAPT (0.35) | CYP19A1LMNAMAPTSTSGSK3A | |
| SCHEMBL4373611 | 0.85 | FNTA (0.46) | CYP19A1MAPTPDE4B | |
| SCHEMBL4068033 | 0.84 | MAPT (0.40) | CYP19A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL4065754 | 0.83 | MEN1 (0.41) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL4062041 | 0.83 | MEN1 (0.43) | NPC1RAB9A | |
| SCHEMBL4061207 | 0.82 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL4069185 | 0.82 | HSP90AA1 (0.42) | SMN1; SMN2LMNAMAPTMAPK1PTGER1 | |
| SCHEMBL4072661 | 0.81 | GSK3B (0.43) | SMN1; SMN2LMNAMAPTHPGDMAPK1 | |
| SCHEMBL4065758 | 0.80 | CYP19A1 (0.41) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |