Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31221485 | 1.00 | OPRM1 (0.55) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL765328 | 1.00 | OPRM1 (0.55) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL29980976 | 0.98 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL537135 | 0.98 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL29980665 | 0.94 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL536677 | 0.94 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL24455261 | 0.90 | OPRM1 (0.60) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL2265705 | 0.82 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL536557 | 0.81 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1GRIN1 | |
| SCHEMBL171507 | 0.81 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969166-A | RUTHENIUM OR MOLYBDENUM CATALYSTS FOR EPOXIDATION OF ALKENES WITH OXYGEN | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-10-19 | — | — | US | claimed |
| EP-0869843-A1 | EPOXIDES PRODUCED BY THE OXIDATION OF OLEFINES WITH AIR OR OXYGEN | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-14 | — | — | EP | claimed |
| WO-1996020788-A1 | EPOXIDES PRODUCED BY THE OXIDATION OF OLEFINES WITH AIR OR OXYGEN | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-11 | — | — | WO | claimed |
| US-8383638-B2 | Aminobenzoquinazolinone M1 receptor positive allosteric modulators | MERCK SHARP & DOHME (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120264761-A1 | Aminobenzoquinazolinone M1 Receptor Positive Allosteric Modulators | MERCK SHARP & DOHME LLC | 2012-10-18 | — | — | US | disclosed |
| EP-2010506-A1 | DIAZEPAN DERIVATIVES MODULATORS OF CHEMOKINE RECEPTORS | F. Hoffmann-Roche AG (CH) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007122103-A1 | DIAZEPAN DERIVATIVES MODULATORS OF CHEMOKINE RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-11-01 | — | — | WO | disclosed |
| EP-1080084-B1 | PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-05-06 | — | — | EP | disclosed |
| CN-1303382-A | Epoxidation process for aryl allyl ethers | DOW CHEMICAL CO (US) | 2001-07-11 | — | — | CN | disclosed |
| EP-1080084-A2 | PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS | THE DOW CHEMICAL COMPANY (US) | 2001-03-07 | — | — | EP | disclosed |
| US-6087513-A | REACTION OF ALLYL ARYL ETHER WITH HYDROGEN PEROXIDE IN THE PRESENCE OF TRANSITION METALS FOR OXIDATION | THE DOW CHEMICAL COMPANY (US) | 2000-07-11 | — | — | US | disclosed |
| WO-1999062894-A2 | PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS | THE DOW CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
| US-5969166-A | RUTHENIUM OR MOLYBDENUM CATALYSTS FOR EPOXIDATION OF ALKENES WITH OXYGEN | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-10-19 | — | — | US | disclosed |
| EP-0869843-A1 | EPOXIDES PRODUCED BY THE OXIDATION OF OLEFINES WITH AIR OR OXYGEN | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996020788-A1 | EPOXIDES PRODUCED BY THE OXIDATION OF OLEFINES WITH AIR OR OXYGEN | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264761-A1 | Aminobenzoquinazolinone M1 Receptor Positive Allosteric Modulators | CHRM1, OPRL1, MTNR1B | OPRM1 5/4885OPRD1 13/4885OPRK1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.