Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18469919 | 0.85 | CCR5 (0.41) | PKMOPRM1HTR1AHTR2AKDM4E | |
| SCHEMBL967470 | 0.83 | — | — | |
| SCHEMBL22241230 | 0.83 | PKM (0.40) | PKMOPRM1HTR1AHTR2AKDM4E | |
| SCHEMBL18469951 | 0.81 | PKM (0.39) | PKMOPRM1HTR1AHTR2AKDM4E | |
| SCHEMBL967276 | 0.81 | L3MBTL1 (0.49) | L3MBTL1 | |
| SCHEMBL18469948 | 0.80 | CCR5 (0.45) | PKMOPRM1HTR1AHTR2ACCR5 | |
| SCHEMBL970095 | 0.79 | L3MBTL1 (0.51) | L3MBTL1 | |
| SCHEMBL18469961 | 0.79 | CCR5 (0.46) | PKMHTR1AHTR2ACCR5 | |
| SCHEMBL18469925 | 0.79 | PKM (0.37) | PKMOPRM1HTR1AHTR2ACCR5 | |
| SCHEMBL967635 | 0.78 | L3MBTL1 (0.54) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515724-B1 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2009-10-21 | — | — | EP | claimed |