Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515117 | 0.86 | TSHR (0.44) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL404243 | 0.81 | TSHR (0.40) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL410941 | 0.79 | LMNA (0.38) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL3027915 | 0.78 | TSHR (0.38) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL418249 | 0.78 | LMNA (0.38) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL403031 | 0.77 | LMNA (0.38) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL446693 | 0.77 | LMNA (0.38) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL3025240 | 0.77 | LMNA (0.42) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL419382 | 0.76 | ALDH1A1 (0.40) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL407557 | 0.76 | TSHR (0.34) | TSHRLMNAHPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| EP-2185564-A2 | TRICYCLIC BRIDGED CYCLOPENTANEDIONE DERIVATIVES AS HERBICIDES | Syngenta Limited (GB) | 2010-05-19 | — | — | EP | disclosed |
| EP-2173755-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009019015-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009019015-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009019005-A2 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009019005-A2 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |