Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688632 | 0.90 | SLC18A3 (0.40) | S100A4TRPV1SLC18A3MAPK1PKM | |
| SCHEMBL28092024 | 0.86 | S100A4 (0.41) | S100A4TRPV1SLC18A3MAPK1PKM | |
| SCHEMBL403033 | 0.80 | SLC18A3 (0.45) | SLC18A3MAPK1PKMHSP90AA1KDM4E | |
| SCHEMBL20856579 | 0.79 | MAPK1 (0.56) | SLC18A3MAPK1TDP1TSHRMEN1 | |
| SCHEMBL31586887 | 0.79 | TSHR (0.58) | SLC18A3KDM4ETDP1TSHRGPR35 | |
| SCHEMBL25385922 | 0.78 | S100A4 (0.41) | S100A4TRPV1SLC18A3MAPK1PKM | |
| SCHEMBL18840406 | 0.77 | ALDH1A1 (0.43) | S100A4TRPV1MAPK1PKMERN1 | |
| SCHEMBL27315627 | 0.77 | S100A4 (0.43) | S100A4TRPV1MAPK1PKMRAB9A | |
| SCHEMBL27430080 | 0.76 | VCAM1 (0.56) | SLC18A3MAPK1TSHRMEN1KMT2A | |
| SCHEMBL31586509 | 0.75 | KAT2B (0.45) | SLC18A3MAPK1HSP90AA1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051717-A1 | COMPOUND AS PLK1 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-03-14 | — | — | WO | disclosed |
| CN-117658987-A | Compounds as PLK1 inhibitors, and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| CN-102291989-B | Herbicide derived from cyclopentanedione | 辛根塔有限公司 | 2016-08-03 | — | — | CN | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| CN-102281759-B | Cyclopentadione derived herbicides | SYNGENTA LTD | 2014-07-23 | — | — | CN | disclosed |
| US-8530388-B2 | Cyclopentadione derived herbicides | SYNGENTA LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| EP-2387310-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | Syngenta Limited (GB) | 2011-11-23 | — | — | EP | disclosed |
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-11-10 | — | — | US | disclosed |
| US-D646956-S1 | TV mount | LEUNG ALEX | 2011-10-18 | — | — | US | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010081894-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010081894-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |
| US-5707989-A | ANTITUMOR AGENTS, INHIBITING SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES | DR. KARL THOMAE GMBH (DE) | 1998-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | DDT, CYP1B1, CYP1A1 | S100A4 3795/4885TRPV1 2161/4885SLC18A3 1949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.