SCHEMBL4064688

SCHEMBL4064688

CN(C(=O)CCc1ccccc1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.67
KMT2A Q03164 5/20 0.64
ALOX5 P09917 2/20 0.57
GAA P10253 3/20 0.55
ALDH1A1 P00352 3/20 0.55
HPGD P15428 1/20 0.55
MEN1 O00255 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
HTT P42858 1/20 0.54
KEAP1 Q14145 1/20 0.53
KDM4E B2RXH2 1/20 0.51
FFAR1 O14842 1/20 0.50
ALOX15 P16050 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8699095 0.90 MLYCD (0.64) MLYCDKMT2AALOX5GAAALDH1A1
SCHEMBL2202823 0.89 KDM4E (0.62) MLYCDKMT2AALOX5GAAALDH1A1
SCHEMBL7335518 0.86 MLYCD (0.71) MLYCDKMT2AALOX5GAAALDH1A1
SCHEMBL18180430 0.86 NPC1 (0.61) MLYCDKMT2AALOX5ALDH1A1L3MBTL1
SCHEMBL2833357 0.83 MLYCD (0.61) MLYCDKMT2AALOX5GAAALDH1A1
SCHEMBL2831110 0.83 MLYCD (0.57) MLYCDKMT2AGAAALDH1A1HPGD
SCHEMBL3366949 0.82 KMT2A (0.70) MLYCDKMT2AALOX5ALDH1A1MEN1
SCHEMBL8782011 0.81 MLYCD (0.49) MLYCDKMT2AALOX5GAAALDH1A1
Water SCHEMBL3678915 0.81 KMT2A (0.68) MLYCDKMT2AALOX5ALDH1A1MEN1
Hydrochloric Acid SCHEMBL3136984 0.81 KMT2A (0.68) MLYCDKMT2AALOX5ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960030-A Preparation method of 3-subunit oxindole derivative 湖北工业大学 2023-04-14 CN claimed
CN-101095648-A Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds OREAL (FR) 2008-01-02 CN claimed
CN-119331033-A Catalyst CudppfBH4And its use in catalyzing the reduction of alpha, beta-unsaturated amides 安徽大学 2025-01-21 CN disclosed
CN-115960030-B Preparation method of 3-subunit oxindole derivative 湖北工业大学 2024-09-27 CN disclosed
CN-115960030-B Preparation method of 3-subunit oxindole derivative 湖北工业大学 2024-09-27 CN disclosed
CN-115960030-A Preparation method of 3-subunit oxindole derivative 湖北工业大学 2023-04-14 CN disclosed
CN-115960030-A Preparation method of 3-subunit oxindole derivative 湖北工业大学 2023-04-14 CN disclosed
CN-111960962-B Nickel-catalyzed alpha-alkylation method of acetamide and thioacetamide 山东师范大学 2023-03-07 CN disclosed
CN-101417972-A 3-methylene-indol-2-one derivates and preparation method thereof UNIV WENZHOU (CN) 2009-04-29 CN disclosed
CN-101417972-A 3-methylene-indol-2-one derivates and preparation method thereof UNIV WENZHOU (CN) 2009-04-29 CN disclosed
EP-1415986-B1 SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS BANYU PHARMA CO LTD (JP) 2009-04-08 EP disclosed
EP-1911438-A2 Cosmetic composition containing a derivative of dibenzoylmethane and a arylalkyl amide or ester compound; method of photostabilising the derivative of dibenzoylmethane L'Oréal (FR) 2008-04-16 EP disclosed
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds L'OREAL (FR) 2008-01-24 US disclosed
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds L'OREAL (FR) 2008-01-24 US disclosed
US-7205417-B2 Spiro compounds BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds TYR, DDT, AADAC MLYCD 1031/4885KMT2A 1285/4885ALOX5 2493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.