Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781896 | 0.85 | TRPM8 (0.59) | KMT2ATRPM8ALDH1A1MEN1ALOX5 | |
| SCHEMBL8781873 | 0.83 | THRA (0.46) | MLYCDPPIBKMT2AALDH1A1KDM4E | |
| SCHEMBL10661439 | 0.82 | CHEK1 (0.46) | GAAHPGDKMT2AALDH1A1KDM4E | |
| SCHEMBL4064688 | 0.81 | MLYCD (0.67) | MLYCDGAAHPGDKMT2AALDH1A1 | |
| SCHEMBL8782100 | 0.76 | APP (0.49) | HPGDKMT2ATRPM8 | |
| SCHEMBL1002974 | 0.74 | FFAR1 (0.53) | ALDH1A1 | |
| SCHEMBL8781764 | 0.74 | TRPM8 (0.56) | GAAHPGDKMT2ATRPM8ALDH1A1 | |
| SCHEMBL8699095 | 0.73 | MLYCD (0.64) | MLYCDGAAHPGDKMT2AALDH1A1 | |
| SCHEMBL2202823 | 0.72 | KDM4E (0.62) | MLYCDGAAHPGDKMT2AALDH1A1 | |
| SCHEMBL7385251 | 0.72 | KMT2A (0.50) | MLYCDGAAPPIBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |