Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025090 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TDP1HTTL3MBTL1TSHR | |
| SCHEMBL7448412 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TDP1HTTL3MBTL1TSHR | |
| SCHEMBL8584218 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1HTTL3MBTL1TSHR | |
| SCHEMBL2875064 | 0.82 | KDM4E (0.62) | ALDH1A1TDP1HTTL3MBTL1TSHR | |
| SCHEMBL5710874 | 0.82 | ALDH1A1 (0.65) | ALDH1A1TDP1HTTL3MBTL1TSHR | |
| SCHEMBL1282917 | 0.82 | ALDH1A1 (0.65) | ALDH1A1TDP1HTTL3MBTL1TSHR | |
| SCHEMBL2135648 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TDP1HTTL3MBTL1TSHR | |
| SCHEMBL7445510 | 0.81 | RAB9A (0.52) | HTTL3MBTL1KMT2ARAB9APOLB | |
| SCHEMBL24729065 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1HTTL3MBTL1TSHR | |
| SCHEMBL5710869 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1HTTL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039886-A4 | HIV/FIV PROTEASE INHIBITORS HAVING A SMALL P3 RESIDUE | SCRIPPS RESEARCH INST (US) | 2001-05-16 | — | — | EP | claimed |
| EP-1039886-A1 | HIV/FIV PROTEASE INHIBITORS HAVING A SMALL P3 RESIDUE | The Cripps Research Institute (US) | 2000-10-04 | — | — | EP | claimed |
| WO-1999029311-A1 | HIV/FIV PROTEASE INHIBITORS HAVING A SMALL P3 RESIDUE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-06-17 | — | — | WO | claimed |
| WO-2009122433-A2 | A PROCESS FOR PREPARATION OF RAMIPRIL | IPCA LABORATORIES LIMITED (IN) | 2009-10-08 | — | — | WO | disclosed |