SCHEMBL4065387

SCHEMBL4065387

Cc1cc(C)c2cccc(OCc3c(Cl)ccc(S(=O)(=O)O)c3Cl)c2n1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 10/20 0.63
RORC P51449 10/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4059811 0.84 BDKRB2 (0.76) BDKRB2
SCHEMBL4058616 0.84 BDKRB2 (0.65) BDKRB2
SCHEMBL4067174 0.82 BDKRB2 (0.68) BDKRB2RORC
SCHEMBL4059073 0.82 BDKRB2 (0.68) BDKRB2RORC
SCHEMBL4487671 0.82 BDKRB2 (0.53) BDKRB2RORC
SCHEMBL5905821 0.81 BDKRB2 (0.74) BDKRB2
SCHEMBL4062473 0.80 BDKRB2 (0.73) BDKRB2
SCHEMBL3743960 0.80 RORC (0.83) BDKRB2RORC
SCHEMBL6946090 0.80 RORC (0.83) BDKRB2RORC
SCHEMBL7805097 0.80 RORC (0.66) BDKRB2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1513531-B1 BASIC NON-PEPTIDE BRADYKININ ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREFROM MENARINI RICERCHE SPA (IT) 2009-10-21 EP claimed
EP-1513531-B1 BASIC NON-PEPTIDE BRADYKININ ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREFROM MENARINI RICERCHE SPA (IT) 2009-10-21 EP disclosed