SCHEMBL4065863

SCHEMBL4065863

Cc1cc(C2(c3ccc(O)c(C)c3)CCC(C(C)C)CC2)ccc1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.63
ESR2 Q92731 5/20 0.63
ACHE P22303 1/20 0.38
TDP1 Q9NUW8 2/20 0.36
TP53 P04637 1/20 0.36
LMNA P02545 4/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
XBP1 P17861 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PDE10A Q9Y233 1/20 0.34
ALOX12 P18054 2/20 0.34
PPARA Q07869 1/20 0.33
OPRL1 P41146 3/20 0.32
OPRM1 P35372 2/20 0.32
OPRD1 P41143 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17636585 0.84 ESR1 (0.58) ESR1ESR2ACHETDP1TP53
SCHEMBL5386114 0.83 ESR1 (0.71) ESR1ESR2ACHETDP1TP53
SCHEMBL2996266 0.82 ACHE (0.58) ESR1ESR2ACHEOPRL1OPRM1
SCHEMBL29393324 0.82 ESR1 (0.69) ESR1ESR2ACHETDP1TP53
SCHEMBL30165897 0.82 ESR1 (0.69) ESR1ESR2ACHETDP1TP53
SCHEMBL4200651 0.82 ESR1 (0.69) ESR1ESR2ACHETDP1TP53
SCHEMBL673329 0.81 ESR1 (0.85) ESR1ESR2ACHETDP1TP53
SCHEMBL12651135 0.81 ESR1 (0.58) ESR1ESR2ACHETDP1TP53
SCHEMBL17636584 0.79 ESR1 (0.65) ESR1ESR2ACHETDP1TP53
SCHEMBL17636582 0.79 ESR1 (0.65) ESR1ESR2ACHETDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11789363-B2 Positive photosensitive resin composition, cured film therefrom, and solid state image sensor comprising the same TORAY INDUSTRIES, INC. (JP) 2023-10-17 US disclosed
US-20210116812-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM THEREFROM, AND SOLID STATE IMAGE SENSOR COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2021-04-22 US disclosed
US-9018338-B2 Polycarbonate resin and molded article thereof TEIJIN LIMITED (JP) 2015-04-28 US disclosed
US-20130253162-A1 POLYCARBONATE RESIN AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2013-09-26 US disclosed
EP-2626376-A1 POLYCARBONATE RESIN AND MOLDED ARTICLE Teijin Chemicals, Ltd. (JP) 2013-08-14 EP disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7442757-B2 Resin, resin composition, method for manufacturing the same, and molded material including the same TORAY INDUSTRIES, INC. (JP) 2008-10-28 US disclosed
US-20070299164-A1 Heatcurable dielectric resin composition and heatcurable dielectric resin film NIPPON PAINT CO., LTD. (JP) 2007-12-27 US disclosed
EP-1688965-A2 Heatcurable dielectric resin composition and heatcurable dielectric resin film Nippon Paint Co., Ltd. (JP) 2006-08-09 EP disclosed
US-20060047104-A1 Resin, resin composition, process for production thereof, and moldings made by using the same TORAY INDUSTRIES, INC. (JP) 2006-03-02 US disclosed
EP-1518884-A1 RESIN, RESIN COMPOSITIONS, PROCESS FOR PRODUCTION THEREOF, AND MOLDINGS MADE BY USING THE SAME TORAY INDUSTRIES, INC. (JP) 2005-03-30 EP disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ESR1 392/4885ESR2 895/4885ACHE 4498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.