Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 4/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20801657 | 0.72 | NOTUM (0.38) | HCAR2SCN4APDPK1LTA4HNOTUM | |
| SCHEMBL87533 | 0.71 | — | — | |
| SCHEMBL3068150 | 0.71 | SCN4A (0.62) | HCAR2SCN4APDPK1LTA4HPOLB | |
| SCHEMBL132285 | 0.69 | — | — | |
| SCHEMBL28099054 | 0.68 | SCN4A (0.43) | HCAR2SCN4APDPK1LTA4HPOLB | |
| SCHEMBL949067 | 0.68 | — | — | |
| SCHEMBL13078874 | 0.67 | METAP2 (0.32) | NPC1RAB9A | |
| SCHEMBL17791787 | 0.67 | HCAR2 (0.61) | HCAR2SCN4APDPK1POLBPTPN11 | |
| SCHEMBL12075153 | 0.67 | SCN4A (0.52) | SCN4APDPK1LTA4HPOLBPTPN11 | |
| Bromide SCHEMBL19459238 | 0.67 | LTA4H (0.47) | HCAR2SCN4APDPK1LTA4HPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009184925-A | 5-(1H-1,2,3-TRIAZOL-4-YL)-1H-PYRAZOLE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 2009-08-20 | — | — | JP | disclosed |
| WO-2008053602-A1 | 5-(1H-1,2,3-TRIAZOL-4-YL)-1H-PYRAZOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-05-08 | — | — | WO | disclosed |