Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.45 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246236 | 0.92 | KIF11 (0.52) | KIF11KIF23GNRHRMC4R | |
| SCHEMBL5740939 | 0.87 | KIF11 (0.47) | KIF11KIF23GNRHRMC4RSMN1; SMN2 | |
| SCHEMBL3957099 | 0.87 | KIF11 (0.57) | KIF11KIF23 | |
| SCHEMBL4059317 | 0.85 | KIF11 (0.63) | KIF11KIF23 | |
| SCHEMBL4066347 | 0.85 | KIF11 (0.64) | KIF11KIF23 | |
| SCHEMBL5247152 | 0.82 | KIF11 (0.52) | KIF11KIF23MC4R | |
| SCHEMBL3961576 | 0.79 | KIF11 (0.57) | KIF11KIF23 | |
| SCHEMBL3905973 | 0.78 | KIF11 (0.51) | KIF11KIF23GNRHRMC4R | |
| SCHEMBL3960561 | 0.78 | KIF11 (0.57) | KIF11KIF23 | |
| SCHEMBL3957584 | 0.78 | KIF11 (0.57) | KIF11KIF23TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781673-B1 | SELECTED FUSED HETEROCYCLICS AND USES THEREOF | ASTRAZENECA AB (SE) | 2009-10-21 | — | — | EP | disclosed |