SCHEMBL4066752

SCHEMBL4066752

C=C(C)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOP(=O)(O)O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
TSHR P16473 7/20 0.44
ALDH1A1 P00352 5/20 0.40
LPAR3 Q9UBY5 6/20 0.36
LPAR2 Q9HBW0 4/20 0.36
LPAR1 Q92633 3/20 0.36
BTN3A1 O00481 1/20 0.36
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4066760 1.00 THRB (0.59) THRBTSHRALDH1A1LPAR3LPAR2
SCHEMBL5424148 1.00 THRB (0.59) THRBTSHRALDH1A1LPAR3LPAR2
SCHEMBL6690732 1.00 THRB (0.59) THRBTSHRALDH1A1LPAR3LPAR2
SCHEMBL2641082 1.00 THRB (0.59) THRBTSHRALDH1A1LPAR3LPAR2
Ammonia Solution, Strong SCHEMBL18140871 0.98 THRB (0.58) THRBTSHRALDH1A1LPAR3LPAR2
Ammonia Solution, Strong SCHEMBL18140250 0.98 THRB (0.58) THRBTSHRALDH1A1LPAR3LPAR2
SCHEMBL41531 0.94 THRB (0.55) THRBTSHRALDH1A1LPAR3LPAR2
SCHEMBL29614442 0.94 THRB (0.55) THRBTSHRALDH1A1LPAR3LPAR2
Ethylene SCHEMBL42784 0.93 THRB (0.53) THRBTSHRALDH1A1LPAR3LPAR2
Ammonia Solution, Strong SCHEMBL18139579 0.93 THRB (0.53) THRBTSHRALDH1A1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140224140-A1 PRINTING METHOD USING LITHOGRAPHIC PRINTING PLATE PRECURSOR OF ON-PRESS DEVELOPMENT TYPE FUJIFILM COPORATION (JP) 2014-08-14 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20120227605-A1 ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING PLATE SUPPORT, PRESENSITIZED PLATE, METHOD OF MANUFACTURING ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE AND METHOD OF MANUFACTURING LITHOGRAPHIC PRINTING PLATE SUPPORT FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20120103220-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR SONOKAWA KOJI (JP) 2012-05-03 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
US-20110159437-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-06-30 US disclosed
US-20110134411-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING METHOD AND PACKAGED BODY OF LITHOGRAPHIC PRINTING PLATE PRECURSORS MITSUMOTO TOMOYOSHI 2011-06-09 US disclosed
US-7939240-B2 Lithographic printing plate precursor and method of producing printing plate FUJIFILM CORPORATION (JP) 2011-05-10 US disclosed
US-20110091814-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS OOHASHI HIDEKAZU 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS FLNA, PFN1, FLNB THRB 3699/4885TSHR 3817/4885ALDH1A1 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.