SCHEMBL76714

SCHEMBL76714

O=C(ON1C(=O)CCC1=O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.48
ALDH1A1 P00352 3/20 0.47
MGLL Q99685 1/20 0.46
SRD5A2 P31213 1/20 0.46
LMNA P02545 4/20 0.44
TSHR P16473 3/20 0.44
NPC1 O15118 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
RAB9A P51151 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44
STAT1 P42224 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
F2 P00734 1/20 0.42
ELANE P08246 2/20 0.42
MEN1 O00255 2/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133554 0.93 KMT2A (0.53) KMT2AALDH1A1MGLLLMNATSHR
SCHEMBL19309377 0.93 KMT2A (0.53) KMT2AALDH1A1MGLLLMNATSHR
SCHEMBL15169078 0.90 KMT2A (0.48) KMT2AMGLLLMNATSHRNPC1
SCHEMBL15169077 0.90 KMT2A (0.48) KMT2AMGLLLMNATSHRNPC1
SCHEMBL13588629 0.90 KMT2A (0.43) KMT2AALDH1A1MGLLSRD5A2LMNA
SCHEMBL300884 0.88 CA12 (0.42) KMT2AALDH1A1MGLLLMNAMAPT
SCHEMBL4872950 0.87 SMN1; SMN2 (0.54) KMT2AMGLLNPC1MAPTHPGD
SCHEMBL27717830 0.84 CA1 (0.55) KMT2AALDH1A1MGLLSRD5A2TSHR
SCHEMBL6705699 0.84 NAAA (0.50) KMT2AALDH1A1SRD5A2SMN1; SMN2MEN1
SCHEMBL5136264 0.84 AKR1C3 (0.49) KMT2AALDH1A1MGLLL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677922-B Dual-functional polymer and modification method 深圳市曙芯生物科技有限公司 2024-01-26 CN claimed
CN-115677922-A Difunctional polymer and modification method 深圳市曙芯生物科技有限公司 2023-02-03 CN claimed
CN-111565707-A Devices and methods for delivering therapeutics 森玛治疗公司 2020-08-21 CN claimed
EP-3638205-A1 DEVICES AND METHODS FOR DELIVERING THERAPEUTICS Semma Therapeutics, Inc. (US) 2020-04-22 EP claimed
WO-2018232180-A1 DEVICES AND METHODS FOR DELIVERING THERAPEUTICS SEMMA THERAPEUTICS, INC. (US) 2018-12-20 WO claimed
EP-2478049-B1 A POLYMER SUPPORT UNIV CAPE TOWN (ZA) 2015-02-25 EP claimed
EP-2333548-B1 Biological indicator AMERICAN STERILIZER CO (US) 2014-07-30 EP claimed
US-8420802-B2 Polymer support UNIVERSITY OF CAPE TOWN (ZA) 2013-04-16 US claimed
EP-2478049-A1 A POLYMER SUPPORT University of Cape Town (ZA) 2012-07-25 EP claimed
US-20120178916-A1 Polymer Support UNIVERSITY OF CAPE TOWN (ZA) 2012-07-12 US claimed
US-8128688-B2 Carbon coating on an implantable device ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-03-06 US claimed
WO-2011083360-A1 A POLYMER SUPPORT UNIVERSITY OF CAPE TOWN (ZA) 2011-07-14 WO claimed
WO-2008002632-A2 CARBON COATING ON AN IMPLANTABLE DEVICE ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2008-01-03 WO claimed
US-20070298354-A1 Carbon coating on an implantable device ABBOTT CARDIOVASCULAR SYSTEMS INC. 2007-12-27 US claimed
EP-4115806-B1 ANALYTE SENSOR AND METHOD FOR MANUFACTURING AN ANALYTE SENSOR ROCHE DIABETES CARE GMBH (DE) 2026-05-20 EP disclosed
CN-122038263-A Expansion method of single cell, single cell nucleus or single subcellular structure and application thereof 浙江大学医学院附属第一医院(浙江省第一医院) 2026-05-15 CN disclosed
US-12607591-B2 Flux-limiting polymer membrane ROCHE DIABETES CARE, INC. (US) 2026-04-21 US disclosed
US-5718915-A DRUG DELIVERY BURSTEIN LABORATORIES, INC. (US) 1998-02-17 US disclosed
WO-1996032841-A9 NOVEL THERAPEUTIC BINDING MOLECULE COMPLEXES 1996-12-27 WO disclosed
WO-1996032841-A1 NOVEL THERAPEUTIC BINDING MOLECULE COMPLEXES BURSTEIN LABORATORIES, INC. (US) 1996-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12607591-B2 Flux-limiting polymer membrane SELP, EPCAM, SELPLG KMT2A 4658/4885ALDH1A1 1834/4885MGLL 1356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.