SCHEMBL4066876

SCHEMBL4066876

CC1=C(C)C(Cl)([SiH2]C2(Cl)C(C)=C(C)c3cc(C(C)(C)C)ccc32)c2ccc(C(C)(C)C)cc21.[Zr]

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28193180 0.72 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL27638685 0.70 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL7007867 0.66
SCHEMBL4313980 0.65 S100A4 (0.30)
SCHEMBL27638764 0.63 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL27627855 0.61 ALDH1A1 (0.39) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL9502981 0.61 ALDH1A1 (0.46) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL3353022 0.61 S100A4 (0.30)
SCHEMBL7263441 0.61 ALDH1A1 (0.38) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL19262047 0.61 ALDH1A1 (0.48) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2045304-A2 Polypropylene-Based Adhesive Compositions ExxonMobil Chemical Patents Inc. (US) 2009-04-08 EP disclosed
EP-1311593-B1 POLYPROPYLENE FILMS EXXONMOBIL CHEM PATENTS INC (US) 2009-01-07 EP disclosed
US-7205363-B2 Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-04-17 US disclosed
EP-1315858-B1 POLYPROPYLENE FIBERS AND FABRICS EXXONMOBIL CHEM PATENTS INC (US) 2007-02-07 EP disclosed
EP-1237957-B1 PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS EXXONMOBIL CHEM PATENTS INC (US) 2006-08-23 EP disclosed
US-6861384-B2 Process for preparation of a salt-like chemical compound and its use in catalyst systems for preparing polyolefins BASELL POLYOLEFINE GMBH (DE) 2005-03-01 US disclosed
US-20040254316-A1 Polymerization processes using antistatic agents EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-16 US disclosed
US-20040171782-A1 Polypropylene polymers EXXONMOBIL CHEMICAL PATENTS INC. 2004-09-02 US disclosed
US-20040110886-A1 Polypropylene-based adhesive compositions KARANDINOS ANTHONY GEORGE (BE) 2004-06-10 US disclosed
US-20040048992-A1 Process for preparation of salt-like chemical compound, and its use in catalyst systems for preparing polyolefins EQUISTAR CHEMICALS, LP 2004-03-11 US disclosed
US-20020169261-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-11-14 US disclosed
EP-1237995-A1 FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE ExxonMobil Chemical Patents Inc. (US) 2002-09-11 EP disclosed
EP-1237957-A1 PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2002-09-11 EP disclosed
US-6395847-B2 COMBINING NUCLEOPHILIC PARTICULATE SUPPORT WITH ARYLBORON OR ARYLALUMINUM LEWIS ACID COMPOUND IN PRESENCE OF LEWIS BASE; CONTACTING PRODUCT OF WITH TRIALKYLALUMINUM COMPOUND; AND, REACTING PRODUCT WITH METALLIC PRECURSOR EXXONMOBIL CHEMICAL PATENTS INC. 2002-05-28 US disclosed
WO-2002016480-A2 POLYPROPYLENE FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
US-20020019507-A1 Polypropylene-based adhesive compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-02-14 US disclosed
US-20010049331-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2001-12-06 US disclosed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US disclosed
WO-2001036499-A1 PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
WO-2001032757-A1 FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040048992-A1 Process for preparation of salt-like chemical compound, and its use in catalyst systems for preparing polyolefins CLIC1, HACL2, RFC1 ALDH1A1 1979/4885NPC1 978/4885PLA2G1B 3960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.