SCHEMBL4066882

SCHEMBL4066882

C=Cc1ccc(-c2ccccc2-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.34
ALDH1A1 P00352 5/20 0.33
HSD17B10 Q99714 2/20 0.33
HPGD P15428 1/20 0.33
BCL2L1 Q07817 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
CYP2A6 P11509 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
MAPK1 P28482 1/20 0.33
TSHR P16473 1/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
HTT P42858 2/20 0.32
PTGS2 P35354 1/20 0.32
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4069489 0.90 ALDH1A1 (0.36) FLT3ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL31577216 0.87 ALDH1A1 (0.38) FLT3ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL4070792 0.87 ALDH1A1 (0.38) FLT3ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL5375695 0.80 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL4075472 0.79 MAOA (0.34) ALDH1A1HPGDHDAC4HDAC2HDAC8
SCHEMBL4067689 0.79 ALDH1A1 (0.40) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL4201594 0.78 ALDH1A1 (0.43) FLT3ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL9613858 0.77 ALDH1A1 (0.39) FLT3ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL8164163 0.77 ALDH1A1 (0.39) FLT3ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL27763811 0.77 BACE1 (0.37) ALDH1A1HSD17B10HPGDBCL2L1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019120-B1 BLOCK COPOLYMERS NIPPON SODA CO (JP) 2016-04-13 EP disclosed
US-8193285-B2 Block copolymers NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
US-20090253867-A1 BLOCK COPOLYMERS NIPPON SODA CO., LTD. (JP) 2009-10-08 US disclosed
EP-2019120-A1 BLOCK COPOLYMERS Nippon Soda Co., Ltd. (JP) 2009-01-28 EP disclosed