Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940424 | 0.87 | SLC6A3 (0.53) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| SCHEMBL1067433 | 0.87 | SLC6A3 (0.53) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| SCHEMBL3790814 | 0.83 | SLC6A3 (0.50) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| SCHEMBL3786501 | 0.83 | HDAC4 (0.52) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| SCHEMBL3783699 | 0.82 | KMO (0.53) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| Ammonia Solution, Strong SCHEMBL7349459 | 0.82 | SLC6A3 (0.49) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| SCHEMBL29557463 | 0.79 | SLC6A3 (0.59) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| SCHEMBL28745939 | 0.79 | SLC6A3 (0.59) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| SCHEMBL16233611 | 0.78 | SLC6A2 (0.46) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A | |
| SCHEMBL8178790 | 0.78 | ESR2 (0.47) | SLC6A3SLC6A2ADRA1ASLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| CN-1538956-A | Spiro compounds | ������ҩ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |