Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786501 | 0.98 | HDAC4 (0.52) | KMOHDAC4HDAC2HDAC8SLC6A2 | |
| SCHEMBL3790814 | 0.94 | SLC6A3 (0.50) | KMOHDAC4HDAC2HDAC8SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL7349459 | 0.92 | SLC6A3 (0.49) | KMOHDAC4HDAC2HDAC8SLC6A2 | |
| SCHEMBL29940424 | 0.89 | SLC6A3 (0.53) | SLC6A2SLC6A3ADRA1ASLC6A4HTR2A | |
| SCHEMBL1067433 | 0.89 | SLC6A3 (0.53) | SLC6A2SLC6A3ADRA1ASLC6A4HTR2A | |
| SCHEMBL31547364 | 0.89 | KMO (0.47) | KMOHDAC4HDAC2HDAC8SLC6A2 | |
| SCHEMBL669730 | 0.87 | KMO (0.64) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL5667650 | 0.87 | KMO (0.64) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL1461329 | 0.85 | KMO (0.42) | KMOHDAC4HDAC2HDAC8SLC6A2 | |
| SCHEMBL5666805 | 0.84 | KMO (0.62) | KMOHDAC4HDAC2HDAC8CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210242-A | Organic molecules for optoelectronic devices | 三星显示有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-10442990-B2 | Mesogenic compounds, liquid crystal media and components for high frequency technology | MERCK PATENT GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| US-9765259-B2 | Mesogenic compounds, liquid-crystalline media and components for high-frequency technology | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9752077-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
| CN-103339225-B | Liquid-crystalline medium, component for high-frequency technology and mesogenic compound | 默克专利股份有限公司 | 2016-12-21 | — | — | CN | disclosed |
| US-9523037-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2016-12-20 | — | — | US | disclosed |
| EP-2688979-B1 | MESOGENIC COMPOUNDS, LIQUID CRYSTAL MEDIA AND COMPONENTS FOR HIGH FREQUENCY TECHNOLOGY | MERCK PATENT GMBH (DE) | 2016-12-07 | — | — | EP | disclosed |
| EP-2665797-B1 | LIQUID CRYSTALLINE MEDIA, COMPONENTS FOR HIGH FREQUENCY TECHNOLOGY AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2688980-B1 | MESOGEN COMPOUNDS, LIQUID CRYSTALLINE MEDIA AND COMPONENTS FOR HIGH FREQUENCY TECHNOLOGY | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-9296948-B2 | Mesogenic compounds, liquid-crystalline media and components for high-frequency technology | MERCK PATENT GMBH (DE) | 2016-03-29 | — | — | US | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| CN-101394847-A | Cycloalkylamines as monoamine reuptake inhibitors | SEPRACOR INC (US) | 2009-03-25 | — | — | CN | disclosed |
| CN-100459274-C | Nonaqueous electrolyte solution and lithium secondary battery | UBE INDUSTRIES (JP) | 2009-02-04 | — | — | CN | disclosed |
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |
| CN-1906794-A | Nonaqueous electrolyte solution and lithium secondary battery | UBE INDUSTRIES (JP) | 2007-01-31 | — | — | CN | disclosed |
| EP-0442115-B1 | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1993-11-24 | — | — | EP | disclosed |
| US-5105036-A | Friedel-Crafts catalyst and oxy-substituted cyclic amidines as cocatylsts; preferential formation of p-isomer | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0442115-A1 | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | KMO 19/4885HDAC4 3220/4885HDAC2 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.