SCHEMBL4067365

SCHEMBL4067365

CC1=Cc2c(C(C)C)cc(C(C)C)cc2C1[Si](C)(C)Cl

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
FABP3 P05413 2/20 0.31
FABP4 P15090 2/20 0.31
ALDH1A1 P00352 1/20 0.31
FABP5 Q01469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5836199 0.88 GABRA1 (0.33) GABRA1GABRB2FABP3FABP4ALDH1A1
SCHEMBL7053482 0.80 LMNA (0.35) GABRA1GABRB2
SCHEMBL6058440 0.79 FABP3 (0.30) FABP3FABP4
SCHEMBL13715054 0.75
SCHEMBL8506274 0.74 GABRA1 (0.35) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL28407141 0.74 GABRA1 (0.35) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL5860017 0.74 GABRA1 (0.35) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27506824 0.74 GABRA1 (0.35) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL5583462 0.74 GABRA1 (0.33) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL9421534 0.74 GABRA1 (0.33) GABRA1GABRB2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622948-B1 PROCESS FOR POLYMERIZING 1-BUTENE BASELL POLYOLEFINE GMBH (DE) 2019-11-20 EP disclosed
US-7579423-B2 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2009-08-25 US disclosed
US-7579423-B2 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2009-08-25 US disclosed
US-20080275254-A1 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2008-11-06 US disclosed
US-20080275254-A1 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2008-11-06 US disclosed
US-7390862-B2 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2008-06-24 US disclosed
US-7390862-B2 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2008-06-24 US disclosed
US-20080139761-A1 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2008-06-12 US disclosed
US-20080139761-A1 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2008-06-12 US disclosed
US-20080132659-A1 Polybutylene or copolymer of butene and ethylene was formed in presence of polymerization catalyst containing a metallocene compound which has a silane group and alumoxane; high molecular weight, high intrinsic viscosity BASELL POLYOLEFINE GMBH (DE) 2008-06-05 US disclosed
US-20080132659-A1 Polybutylene or copolymer of butene and ethylene was formed in presence of polymerization catalyst containing a metallocene compound which has a silane group and alumoxane; high molecular weight, high intrinsic viscosity BASELL POLYOLEFINE GMBH (DE) 2008-06-05 US disclosed
US-20060235173-A1 homopolymerizing or copolymerizing butene and ethylene in presence of polymerization catalyst containing a metallocene compound which has a silane group and alumoxane; high molecular weight, high intrinsic viscosity BASELL POLYOLEFINE GMBH (DE) 2006-10-19 US disclosed
EP-1622948-A2 PROCESS FOR POLYMERIZING 1-BUTENE Basell Polyolefine GmbH (DE) 2006-02-08 EP disclosed
WO-2004099269-A2 PROCESS FOR POLYMERIZING 1-BUTENE BASELL POLYOLEFINE GMBH (DE) 2004-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275254-A1 Process for polymerizing 1-butene C9, CHRM1, C1S GABRA1 801/4885GABRB2 1679/4885FABP3 4866/4885
US-20080139761-A1 Process for polymerizing 1-butene C9, CHRM1, C1S GABRA1 801/4885GABRB2 1679/4885FABP3 4866/4885
US-20060235173-A1 homopolymerizing or copolymerizing butene and ethylene in presence of polymerization catalyst containing a metallocene compound which has a silane group and alumoxane; high molecular weight, high intrinsic viscosity HRH1, F12, HRH3 GABRA1 1369/4885GABRB2 2424/4885FABP3 4858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.