Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291421 | 0.94 | DRD2 (0.49) | DRD2KDM1AMAOAMAOBCA12 | |
| SCHEMBL25187440 | 0.90 | DRD2 (0.47) | DRD2KDM1AMAOAMAOBCA12 | |
| SCHEMBL9182181 | 0.89 | DRD2 (0.47) | DRD2KDM1AMAOAMAOBCA12 | |
| SCHEMBL9182176 | 0.89 | DRD2 (0.47) | DRD2KDM1AMAOAMAOBCA12 | |
| SCHEMBL1515026 | 0.87 | DRD2 (0.59) | DRD2KDM1AMAOAMAOBCA12 | |
| SCHEMBL9291383 | 0.83 | ALDH1A1 (0.54) | CA1CA2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1515040 | 0.83 | DRD2 (0.56) | DRD2KDM1AMAOAMAOBCA12 | |
| SCHEMBL2095118 | 0.83 | ALDH1A1 (0.56) | DRD2KDM1AMAOAMAOBCA12 | |
| SCHEMBL1992931 | 0.81 | ALDH1A1 (0.59) | DRD2KDM1AMAOAMAOBCA12 | |
| SCHEMBL1990897 | 0.81 | ALDH1A1 (0.59) | DRD2KDM1AMAOAMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-105637418-B | Negative working lithographic plate precursor | 伊斯曼柯达公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-109952300-A | As indoleamine 2, imidazo [1,5-a] pyridine of the novel 5 or 8- substitution of 3- dioxygenase enzyme and/or tryptophan 2,3- dioxygenase enzyme selectivity inhibitor | 百济神州有限公司 | 2019-06-28 | — | — | CN | disclosed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| US-5380462-A | Cyclohexyl alkenoate compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-01-10 | — | — | US | disclosed |
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |