Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16905177 | 0.79 | PTGDR (0.40) | KDM1AKDM1BPTGDRPTGDR2SLC6A4 | |
| SCHEMBL402737 | 0.74 | KDM1A (0.42) | KDM1AKDM1BPTGDRPTGDR2SLC6A4 | |
| SCHEMBL29739167 | 0.74 | KDM1A (0.58) | KDM1AKDM1B | |
| SCHEMBL18013231 | 0.74 | HTT (0.40) | KDM1AKDM1BPTGDRPTGDR2 | |
| SCHEMBL30809664 | 0.74 | ALOX15 (0.43) | KDM1AKDM1BPTGDRPTGDR2HTR2A | |
| SCHEMBL2382287 | 0.74 | ALOX15 (0.43) | KDM1AKDM1BPTGDRPTGDR2HTR2A | |
| SCHEMBL16954127 | 0.74 | KDM1A (0.36) | KDM1AKDM1BPTGDRPTGDR2SLC6A4 | |
| SCHEMBL30169705 | 0.74 | NOTUM (0.41) | KDM1AKDM1BSLC6A4HTR2CMAPK1 | |
| SCHEMBL21767417 | 0.74 | CHRNB2 (0.41) | KDM1AKDM1BPTGDR2SLC6A4NOS3 | |
| SCHEMBL16954130 | 0.74 | NOTUM (0.41) | KDM1AKDM1BSLC6A4HTR2CMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| CN-102291989-B | Herbicide derived from cyclopentanedione | 辛根塔有限公司 | 2016-08-03 | — | — | CN | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| CN-102281759-B | Cyclopentadione derived herbicides | SYNGENTA LTD | 2014-07-23 | — | — | CN | disclosed |
| US-8530388-B2 | Cyclopentadione derived herbicides | SYNGENTA LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-8530388-B2 | Cyclopentadione derived herbicides | SYNGENTA LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-8530388-B2 | Cyclopentadione derived herbicides | SYNGENTA LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| EP-2389066-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | Syngenta Limited (GB) | 2011-11-30 | — | — | EP | disclosed |
| EP-2387310-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | Syngenta Limited (GB) | 2011-11-23 | — | — | EP | disclosed |
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-11-10 | — | — | US | disclosed |
| US-D646956-S1 | TV mount | LEUNG ALEX | 2011-10-18 | — | — | US | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010081894-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010081894-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | DDT, CYP1B1, CYP1A1 | KDM1A 751/4885KDM1B 1158/4885CYP2A6 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.