Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999756 | 0.91 | CES2 (0.53) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL29130635 | 0.89 | CES2 (0.52) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL1150848 | 0.81 | LMNA (0.44) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL22367586 | 0.81 | CES2 (0.44) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL7543173 | 0.78 | CES2 (0.44) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL4067604 | 0.77 | LMNA (0.45) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL4809206 | 0.74 | PGR (0.46) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL7542392 | 0.73 | LMNA (0.42) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL7542397 | 0.73 | SLC6A2 (0.42) | LMNACES2CES1SLC6A2SLC6A4 | |
| SCHEMBL28301980 | 0.73 | KDM4E (0.42) | LMNAKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2878591-B1 | RADICALLY CURABLE COMPOUND, METHOD FOR PRODUCING RADICALLY CURABLE COMPOUND, RADICALLY CURABLE COMPOSITION, CURED PRODUCT THEREOF, AND COMPOSITION FOR RESIST MATERIAL | DAINIPPON INK & CHEMICALS (JP) | 2020-09-16 | — | — | EP | disclosed |
| EP-1302514-B1 | Active energy ray-curable antistatic coating composition | MITSUBISHI CHEM CORP (JP) | 2009-07-15 | — | — | EP | disclosed |