Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | GSR | P00390 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | GRM8 | O00222 | 2/20 | 0.58 |
| ▸ | GRM6 | O15303 | 2/20 | 0.58 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL4067712 | 1.00 | PMP22 (0.83) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL29087468 | 0.98 | PMP22 (0.79) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL28103475 | 0.98 | PMP22 (0.79) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL29087469 | 0.98 | PMP22 (0.79) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL28103476 | 0.98 | PMP22 (0.79) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL28099453 | 0.92 | PMP22 (0.76) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL31412696 | 0.92 | PMP22 (0.76) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL411575 | 0.91 | KMT2A (1.00) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL5580393 | 0.91 | KMT2A (1.00) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL994966 | 0.91 | KMT2A (1.00) | PMP22KMT2AALOX15BLMGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10813305-B2 | Regeneration and transformation of Cosmos Bipinnatus plantlets | NOVIN GITI GENE R&D CENTER (N.G.G.) (IR) | 2020-10-27 | — | — | US | claimed |
| US-20170231177-A1 | REGENERATION AND TRANSFORMATION OF COSMOS BIPINNATUS PLANTLETS | Novin Giti Gene R&D Center (N.G.G) (IR) | 2017-08-17 | — | — | US | claimed |
| CN-107835852-B | Controlled foam break up rate in hard surface cleaners | 艺康美国股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| US-20210393497-A1 | ANTIMICROBIAL COMPOSITIONS CONTAINING SOLVENTS INCLUDING A C3-C5 N-ALKYL-GAMMA-BUTYROLACTAM | VIROX TECHNOLOGIES INC. (CA) | 2021-12-23 | — | — | US | disclosed |
| US-20210386066-A1 | C3-C5 N-ALKYL-GAMMA-BUTYROLACTAM CONTAINING ANTIMICROBIAL COMPOSITIONS AND METHODS OF USING SAME | VIROX TECHNOLOGIES INC. (CA) | 2021-12-16 | — | — | US | disclosed |
| US-20210315207-A1 | C3-C5 N-ALKYL-GAMMA-BUTYROLACTAM-CONTAINING ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | VIROX TECHNOLOGIES INC. (CA) | 2021-10-14 | — | — | US | disclosed |
| US-20210307327-A1 | C3-C5 N-ALKYL-GAMMA-BUTYROLACTAM-CONTAINING AN ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | VIROX TECHNOLOGIES INC. (CA) | 2021-10-07 | — | — | US | disclosed |
| CN-113260419-A | Indazolyl cyanoethylamino compounds, compositions thereof, methods of making the same, and methods of using the same | 勃林格殷格翰动物保健美国公司 | 2021-08-13 | — | — | CN | disclosed |
| EP-2203222-B1 | INJECTABLE DERMATOLOGICAL COMPOSITION FOR TREATMENT OF WRINKLES | ITALFARMACIA S R L (IT) | 2021-08-04 | — | — | EP | disclosed |
| CN-108055825-B | Extended release injectable formulations comprising isoxazoline active agents, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2021-03-30 | — | — | CN | disclosed |
| US-10813305-B2 | Regeneration and transformation of Cosmos Bipinnatus plantlets | NOVIN GITI GENE R&D CENTER (N.G.G.) (IR) | 2020-10-27 | — | — | US | disclosed |
| CN-1694958-A | Gene expression system based on codon translation efficiency | UNIV QUEENSLAND (AU) | 2005-11-09 | — | — | CN | disclosed |
| CN-1643135-A | Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same | STEMRON INC (US) | 2005-07-20 | — | — | CN | disclosed |
| CN-1197587-C | Application of position-N desulfurizing heparin in preventing and treating inflammation | SHANGHAI INST OF CYTOBIOLOGY C (CN) | 2005-04-20 | — | — | CN | disclosed |
| CN-1327795-A | Application of position-N desulfurizing heparin in preventing and treating inflammation | SHANGHAI INST OF CYTOBIOLOGY C (CN) | 2001-12-26 | — | — | CN | disclosed |
| CN-1325441-A | Modified exosomes and uses | INST NAT SANTE ET DELA RECH ME (FR) | 2001-12-05 | — | — | CN | disclosed |
| CN-1178554-A | chemically modified interperon | AMGEN INC (US) | 1998-04-08 | — | — | CN | disclosed |
| EP-0658188-A4 | LIQUID OR GEL DETERGENT COMPOSITIONS CONTAINING CALCIUM AND STABILIZING AGENT THEREOF. | PROCTER & GAMBLE (US) | 1995-08-09 | — | — | EP | disclosed |
| EP-0658188-A1 | LIQUID OR GEL DETERGENT COMPOSITIONS CONTAINING CALCIUM AND STABILIZING AGENT THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 1995-06-21 | — | — | EP | disclosed |
| WO-1994005758-A1 | LIQUID OR GEL DETERGENT COMPOSITIONS CONTAINING CALCIUM AND STABILIZING AGENT THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315207-A1 | C3-C5 N-ALKYL-GAMMA-BUTYROLACTAM-CONTAINING ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | C5, C9, C3AR1 | PMP22 939/4885KMT2A 2963/4885ALOX15 14/4885 |
| US-20210393497-A1 | ANTIMICROBIAL COMPOSITIONS CONTAINING SOLVENTS INCLUDING A C3-C5 N-ALKYL-GAMMA-BUTYROLACTAM | EBP, C5, CPS1 | PMP22 1894/4885KMT2A 4289/4885ALOX15 59/4885 |
| US-20210307327-A1 | C3-C5 N-ALKYL-GAMMA-BUTYROLACTAM-CONTAINING AN ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | C5, C9, C1S | PMP22 381/4885KMT2A 3806/4885ALOX15 26/4885 |
| US-20210386066-A1 | C3-C5 N-ALKYL-GAMMA-BUTYROLACTAM CONTAINING ANTIMICROBIAL COMPOSITIONS AND METHODS OF USING SAME | C5, C1S, C9 | PMP22 479/4885KMT2A 4078/4885ALOX15 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.