Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | GSR | P00390 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | GRM8 | O00222 | 2/20 | 0.58 |
| ▸ | GRM6 | O15303 | 2/20 | 0.58 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL4067710 | 1.00 | PMP22 (0.83) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL29087468 | 0.98 | PMP22 (0.79) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL28103475 | 0.98 | PMP22 (0.79) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL29087469 | 0.98 | PMP22 (0.79) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL28103476 | 0.98 | PMP22 (0.79) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL28099453 | 0.92 | PMP22 (0.76) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL31412696 | 0.92 | PMP22 (0.76) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL411575 | 0.91 | KMT2A (1.00) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL5580393 | 0.91 | KMT2A (1.00) | PMP22KMT2AALOX15BLMGSR | |
| Glutamine SCHEMBL994966 | 0.91 | KMT2A (1.00) | PMP22KMT2AALOX15BLMGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10813305-B2 | Regeneration and transformation of Cosmos Bipinnatus plantlets | NOVIN GITI GENE R&D CENTER (N.G.G.) (IR) | 2020-10-27 | — | — | US | claimed |
| US-20170231177-A1 | REGENERATION AND TRANSFORMATION OF COSMOS BIPINNATUS PLANTLETS | Novin Giti Gene R&D Center (N.G.G) (IR) | 2017-08-17 | — | — | US | claimed |
| CN-107835852-B | Controlled foam break up rate in hard surface cleaners | 艺康美国股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-113260419-A | Indazolyl cyanoethylamino compounds, compositions thereof, methods of making the same, and methods of using the same | 勃林格殷格翰动物保健美国公司 | 2021-08-13 | — | — | CN | disclosed |
| EP-2203222-B1 | INJECTABLE DERMATOLOGICAL COMPOSITION FOR TREATMENT OF WRINKLES | ITALFARMACIA S R L (IT) | 2021-08-04 | — | — | EP | disclosed |
| US-10813305-B2 | Regeneration and transformation of Cosmos Bipinnatus plantlets | NOVIN GITI GENE R&D CENTER (N.G.G.) (IR) | 2020-10-27 | — | — | US | disclosed |
| US-20170231177-A1 | REGENERATION AND TRANSFORMATION OF COSMOS BIPINNATUS PLANTLETS | Novin Giti Gene R&D Center (N.G.G) (IR) | 2017-08-17 | — | — | US | disclosed |
| EP-2033689-A1 | Injectable dermatological composition for treatment of the wrinkles | Italfarmacia S.r.l. (IT) | 2009-03-11 | — | — | EP | disclosed |
| EP-1680396-A1 | NOVEL MOLECULE FOR INDUCING DIFFERENTIATION OF DENDRITIC CELLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005037775-A1 | NOVEL MOLECULE FOR INDUCING DIFFERENTIATION OF DENDRITIC CELLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-04-28 | — | — | WO | disclosed |
| EP-0658188-A4 | LIQUID OR GEL DETERGENT COMPOSITIONS CONTAINING CALCIUM AND STABILIZING AGENT THEREOF. | PROCTER & GAMBLE (US) | 1995-08-09 | — | — | EP | disclosed |
| EP-0658188-A1 | LIQUID OR GEL DETERGENT COMPOSITIONS CONTAINING CALCIUM AND STABILIZING AGENT THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 1995-06-21 | — | — | EP | disclosed |
| WO-1994005758-A1 | LIQUID OR GEL DETERGENT COMPOSITIONS CONTAINING CALCIUM AND STABILIZING AGENT THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-17 | — | — | WO | disclosed |