SCHEMBL4068014

SCHEMBL4068014

C[C@H](NC(=O)c1ccccc1)C(=O)NCNC(=O)[C@H](C)NC(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.56
ALDH1A1 P00352 1/20 0.51
RAB9A P51151 1/20 0.51
HPGD P15428 1/20 0.51
CTSL P07711 4/20 0.51
CTSS P25774 2/20 0.51
CTSK P43235 2/20 0.51
CTSB P07858 1/20 0.51
LMNA P02545 1/20 0.51
GFER P55789 1/20 0.51
GPR139 Q6DWJ6 2/20 0.49
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28231704 0.87 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1RAB9AHPGDCTSL
SCHEMBL28231702 0.87 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1RAB9AHPGDCTSL
SCHEMBL11517236 0.85 SMN1; SMN2 (0.52) GAASMN1; SMN2ALDH1A1RAB9AHPGD
SCHEMBL4075735 0.83 ALDH1A1 (0.61) GAASMN1; SMN2ALDH1A1RAB9AHPGD
SCHEMBL7413732 0.82 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1RAB9AHPGDLMNA
SCHEMBL28743340 0.82 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1RAB9AHPGDLMNA
SCHEMBL3658406 0.82 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1RAB9AHPGDCTSL
SCHEMBL11431508 0.81 SMN1; SMN2 (0.57) SMN1; SMN2LMNAGFERGPR139
SCHEMBL10040931 0.80 CTSL (0.60) GAASMN1; SMN2ALDH1A1RAB9AHPGD
SCHEMBL2796740 0.80 CA1 (0.62) SMN1; SMN2ALDH1A1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207107-B2 Di-amido gellant for use in consumer product compositions THE PROCTER & GAMBLE COMPANY (US) 2012-06-26 US disclosed
US-8168579-B2 Fluid detergent compositions comprising a di-amido gellant, and processes for making THE PROCTER AND GAMBLE COMPANY (US) 2012-05-01 US disclosed
US-20110220536-A1 Fluid Detergent Compositions Comprising a Di-Amido Gellant, and Processes for Making THE PROCTER & GAMBLE COMPANY 2011-09-15 US disclosed
US-20110224455-A1 Di-Amido Gellant For Use In Consumer Product Compositions THE PROCTER & GAMBLE COMPANY 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224455-A1 Di-Amido Gellant For Use In Consumer Product Compositions DAGLA, GNPAT, CDIPT GAA 661/4885SMN1; SMN2 3740/4885ALDH1A1 1506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.