Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060686 | 0.82 | POLB (0.44) | P2RX3P2RX2KCNH2CETPPOLB | |
| SCHEMBL4061577 | 0.81 | P2RX3 (0.48) | P2RX3P2RX2KCNH2CETPPOLB | |
| SCHEMBL4061598 | 0.77 | P2RX3 (0.62) | P2RX3P2RX2POLBGAAGFER | |
| SCHEMBL765434 | 0.76 | GAA (0.43) | P2RX3P2RX2KCNH2POLBGAA | |
| SCHEMBL9945955 | 0.74 | RXRA (0.41) | KCNH2MAOAMAOB | |
| SCHEMBL9945952 | 0.74 | KCNH2 (0.40) | KCNH2MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL24306428 | 0.74 | NFE2L2 (0.46) | KCNH2GAAMAOAMAOBMAPT | |
| SCHEMBL8119851 | 0.72 | NFE2L2 (0.43) | P2RX3P2RX2KCNH2POLBGAA | |
| SCHEMBL24414090 | 0.72 | GAA (0.48) | P2RX3P2RX2POLBGAAGFER | |
| SCHEMBL17861691 | 0.72 | GAA (0.50) | P2RX3P2RX2POLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |