Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.69 |
| ▸ | MAOA | P21397 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PRF1 | P14222 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22284 | 0.83 | MAOA (1.00) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL29448271 | 0.83 | MAOA (1.00) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL6903786 | 0.83 | MAOA (1.00) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL6353583 | 0.83 | MAOA (1.00) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL11522370 | 0.83 | MAOA (1.00) | MAOBMAOAALDH1A1KDM4EHPGD | |
| Methyl Alcohol SCHEMBL28318378 | 0.81 | MAOA (0.87) | MAOBMAOAALDH1A1KDM4EHPGD | |
| Bromide SCHEMBL7149637 | 0.81 | MAOA (0.95) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL1364742 | 0.81 | MAOA (0.95) | MAOBMAOAALDH1A1KDM4EHPGD | |
| Methane SCHEMBL11197593 | 0.81 | MAOA (0.95) | MAOBMAOAALDH1A1KDM4EHPGD | |
| Ammonia Solution, Strong SCHEMBL11292618 | 0.81 | MAOA (0.95) | MAOBMAOAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504423-B2 | α-amino acid derivatives and use thereof as medicines | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| US-20070049619-A1 | Alpha-amino acid derivatives and use thereof as medicines | MITSUBISHI PHAMA CORPORATION (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1695969-A1 | ALPHA-AMINO ACID DERIVATIVES AND USE THEREOF AS MEDICINES | Mitsubishi Pharma Corporation (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20060054290-A1 | Novel catalytic activities of oxidoreductases for oxidation and or bleaching | CALL HANS-PETER | 2006-03-16 | — | — | US | disclosed |
| US-6008386-A | ALPHA-AMINO ACIDS BEARING AN OXIRANE RING ON THE ALPHA CARBON IN PLACE OF THE ALPHA-PROTON; IRREVERSIBLE INHIBITORS FOR AMINO ACID DECARBOXYLASES | BOARD OF REGENTS UNIVERSITY OF NEBRASKA-LINCOLN (US) | 1999-12-28 | — | — | US | disclosed |
| US-5705660-A | Method for the synthesis of α-oxiranyl amino acids | BOARD OF REGENTS, UNIVERSITY OF NEBRASKA-LINCOLN | 1998-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049619-A1 | Alpha-amino acid derivatives and use thereof as medicines | DPP4, DPP7, DPP3 | MAOB 2084/4885MAOA 1563/4885ALDH1A1 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.