Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 1.00 |
| ▸ | MAOB | P27338 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TYMS | P04818 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PRF1 | P14222 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353583 | 1.00 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL11522370 | 1.00 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL22284 | 1.00 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL29448271 | 1.00 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Water SCHEMBL11007472 | 0.98 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Methane SCHEMBL11197593 | 0.98 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Fluoride SCHEMBL8592140 | 0.98 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Benzene SCHEMBL18492989 | 0.98 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL11215152 | 0.98 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL12540036 | 0.98 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | claimed |
| EP-0272583-B1 | 5-SUBSTITUTED AMINO-4-HYDROXY-PENTENOIC ACID DERIVATIVES AND THEIR USE | Banyu Pharmaceutical Co., Ltd. (JP) | 1993-09-15 | — | — | EP | claimed |
| EP-0173899-B1 | 2,3-DIHYDROBENZOFURAN-5-SULFONAMIDE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1991-12-18 | — | — | EP | claimed |
| US-4927565-A | HYPOTENSIVE AGENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-05-22 | — | — | US | claimed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | claimed |
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | claimed |
| EP-0272583-A2 | 5-Substituted amino-4-hydroxy-pentenoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-06-29 | — | — | EP | claimed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | claimed |
| EP-0173899-A2 | 2,3-Dihydrobenzofuran-5-sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1986-03-12 | — | — | EP | claimed |
| US-20040198781-A1 | Carbonic anhydrase inhibitor | PHARMACIA CORPORATION | 2004-10-07 | — | — | US | disclosed |
| EP-1414522-A2 | CARBONIC ANHYDRASE INHIBITORS | Pharmacia Corporation (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20030100594-A1 | Carbonic anhydrase inhibitor | PHARMACIA CORPORATION | 2003-05-29 | — | — | US | disclosed |
| WO-2003013655-A2 | CARBONIC ANHYDRASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |
| US-5506356-A | RENIN INHIBITORS; HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |
| US-4677100-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| CN-85109769-A | The preparation of cephalosporins derivatives and application | — | 1986-12-17 | — | — | CN | disclosed |
| EP-0186187-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0173899-A2 | 2,3-Dihydrobenzofuran-5-sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1986-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100594-A1 | Carbonic anhydrase inhibitor | CA2, CA4, CA9 | MAOA 910/4885MAOB 1325/4885ALDH1A1 338/4885 |
| US-20040198781-A1 | Carbonic anhydrase inhibitor | CA2, CA4, CA9 | MAOA 910/4885MAOB 1325/4885ALDH1A1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.