SCHEMBL4068917

SCHEMBL4068917

[C]c1cccc(C(C)(C)c2ccccc2)c1C(C)(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.39
ESR2 Q92731 4/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35
MAPK1 P28482 1/20 0.34
NR3C2 P08235 3/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALOX15 P16050 1/20 0.32
P2RX7 Q99572 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
KCNN4 O15554 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10634183 0.82 ESR1 (0.41) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL11829661 0.77 ESR1 (0.39) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL982955 0.77 ESR1 (0.48) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL15105312 0.77 ALDH1A1 (0.39) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL28101263 0.77 NR3C2 (0.40) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL2199266 0.76 ALDH1A1 (0.54) ESR1ESR2ALDH1A1CYP3A4MAPK1
SCHEMBL28796300 0.76 ESR1 (0.38) ESR1ESR2ALDH1A1CYP3A4CNR1
Toluene SCHEMBL27928703 0.75 CNR1 (0.48) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL10633765 0.74 CRHBP (0.39) ESR1ESR2ALDH1A1CYP3A4MAPK1
Bicarbonate SCHEMBL17164627 0.73 ESR1 (0.44) ESR1ESR2ALDH1A1CYP3A4CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2134779-A1 POLYCARBONATE COMPOSITION CONTAINING UV ABSORBER Bayer MaterialScience AG (DE) 2009-12-23 EP disclosed
EP-2081974-A1 POLYCARBONATES AND COPOLYCARBONATES WITH IMPROVED METAL ADHESION Bayer MaterialScience AG (DE) 2009-07-29 EP disclosed
WO-2008107095-A1 POLYCARBONATE COMPOSITION CONTAINING UV ABSORBER BAYER MATERIALSCIENCE AG (DE) 2008-09-12 WO disclosed
WO-2008037364-A1 POLYCARBONATES AND COPOLYCARBONATES WITH IMPROVED METAL ADHESION BAYER MATERIALSCIENCE AG (DE) 2008-04-03 WO disclosed