Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 8/20 | 0.53 |
| ▸ | MMP12 | P39900 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16898118 | 0.82 | BMP1 (0.68) | BMP1MMP12CTSLCTSSCTSK | |
| SCHEMBL16898117 | 0.82 | BMP1 (0.68) | BMP1MMP12CTSLCTSSCTSK | |
| SCHEMBL6757298 | 0.81 | MMP1 (0.42) | RAB9ACTSLCTSSCTSKPOLB | |
| SCHEMBL4069000 | 0.81 | BMP1 (0.72) | BMP1MMP12ALDH1A1TP53HPGD | |
| SCHEMBL18377827 | 0.74 | MEN1 (0.48) | BMP1MMP12CTSLCTSS | |
| SCHEMBL18378799 | 0.73 | BMP1 (0.49) | BMP1MMP12CTSLCTSS | |
| SCHEMBL6023714 | 0.73 | BMP1 (0.62) | BMP1MMP12RAB9AALDH1A1HPGD | |
| SCHEMBL6237132 | 0.73 | HPGD (0.46) | BMP1RAB9AALDH1A1TP53HPGD | |
| SCHEMBL4071620 | 0.72 | — | — | |
| SCHEMBL13911532 | 0.70 | MAPT (0.52) | RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585757-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-04-22 | — | — | EP | claimed |
| JP-2006516120-A | — | — | 2006-06-22 | — | — | JP | claimed |
| EP-1585757-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-10-19 | — | — | EP | claimed |
| WO-2004052919-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | claimed |
| EP-1585757-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1585757-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004052919-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |