Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 11/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.47 |
| ▸ | LPL | P06858 | 3/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658657 | 0.77 | LPL (0.59) | LPLLIPGTDP1L3MBTL1 | |
| SCHEMBL3933762 | 0.76 | SPHK2 (0.48) | SPHK2SPHK1LPLLIPGTDP1 | |
| SCHEMBL28079356 | 0.75 | LPL (0.61) | LPLLIPGTDP1L3MBTL1 | |
| SCHEMBL95836 | 0.72 | SPHK2 (0.57) | SPHK2SPHK1LPLLIPG | |
| SCHEMBL6059834 | 0.72 | LPL (0.54) | LPLLIPG | |
| SCHEMBL3790301 | 0.71 | SPHK2 (0.50) | SPHK2SPHK1LPLLIPGTDP1 | |
| SCHEMBL199210 | 0.71 | LPL (0.52) | LPLLIPGTDP1L3MBTL1 | |
| SCHEMBL8518305 | 0.71 | LPL (0.66) | LPLLIPGTDP1L3MBTL1 | |
| SCHEMBL3126881 | 0.71 | LPL (0.56) | LPLLIPG | |
| SCHEMBL27694667 | 0.71 | LPL (0.56) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |