SCHEMBL3933762 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	SPHK2	Q9NRA0	11/20	0.48

▸	SPHK1	Q9NYA1	9/20	0.48

▸	LPL	P06858	3/20	0.43

▸	LIPG	Q9Y5X9	3/20	0.43

▸	HSD11B1	P28845	1/20	0.40

▸	TDP1	Q9NUW8	1/20	0.40

▸	L3MBTL1	Q9Y468	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4400096	0.82	KDM4E (0.46)	SPHK2SPHK1HSD11B1
SCHEMBL4401356	0.79	RAB9A (0.47)	SPHK2SPHK1HSD11B1L3MBTL1
SCHEMBL9658657	0.78	LPL (0.59)	LPLLIPGHSD11B1TDP1L3MBTL1
SCHEMBL4069019	0.76	SPHK2 (0.47)	SPHK2SPHK1LPLLIPGTDP1
SCHEMBL28079356	0.76	LPL (0.61)	LPLLIPGTDP1L3MBTL1
SCHEMBL94884	0.74	SPHK2 (0.56)	SPHK2SPHK1LPLLIPG
SCHEMBL94883	0.74	SPHK2 (0.54)	SPHK2SPHK1LPLLIPG
SCHEMBL6059834	0.73	LPL (0.54)	LPLLIPGHSD11B1
SCHEMBL3790301	0.72	SPHK2 (0.50)	SPHK2SPHK1LPLLIPGTDP1
SCHEMBL199210	0.72	LPL (0.52)	LPLLIPGHSD11B1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2043644-A1	NF- B INHIBITOR	Otsuka Pharmaceutical Co., Ltd. (JP)	2009-04-08	—	—	EP	disclosed
WO-2008010601-A1	NF- &kappav;B INHIBITOR	OTSUKA PHARMACEUTICAL CO., LTD. (JP)	2008-01-24	—	—	WO	disclosed