SCHEMBL9898069

SCHEMBL9898069

CC/C=C/c1ccccc1O[PH](=O)Oc1ccccc1/C=C/CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.39
TFEB P19484 1/20 0.38
KDM4E B2RXH2 4/20 0.37
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
TRPA1 O75762 1/20 0.36
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35
GRIK3 Q13003 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
CDK4 P11802 2/20 0.35
CCND1 P24385 2/20 0.35
CCNB2 O95067 1/20 0.35
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
CCNB3 Q8WWL7 1/20 0.35
NR1H3 Q13133 1/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898071 0.87 NFE2L2 (0.41) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL10781099 0.80 NFE2L2 (0.41) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL257125 0.78 NFE2L2 (0.58) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL5085210 0.78 NFE2L2 (0.58) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL29372144 0.78 NFE2L2 (0.58) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL406911 0.76 SRC (0.42) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL73693 0.75 AR (0.46) NFE2L2KDM4EALDH1A1TSHRTRPA1
SCHEMBL12134526 0.75 AR (0.46) NFE2L2KDM4EALDH1A1TSHRTRPA1
SCHEMBL23841293 0.74 AR (0.43) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL3364660 0.74 ALDH1A1 (0.57) KDM4EALDH1A1TSHRSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2474561-B1 METHOD FOR RECYCLING OF PHENOLIC ANTIOXIDANT AGENT, PROCESS FOR PRODUCTION OF OLEFIN POLYMER, POLYOLEFIN POWDER, AND FIBERS ADEKA CORP (JP) 2017-12-27 EP disclosed
EP-2484725-B1 POLYESTER RESIN COMPOSITION, POLYESTER FIBER, POLYESTER RESIN MOLDED ARTICLE, AND PROCESS FOR PRODUCTION OF NUCLEATING AGENT FOR POLYESTER RESIN ADEKA CORP (JP) 2017-07-19 EP disclosed
US-20140275414-A1 METHOD FOR RECYCLING OF PHENOLIC ANTIOXIDANT AGENT, PROCESS FOR PRODUCTION OF OLEFIN POLYMER, POLYOLEFIN POWDER, AND FIBERS ADEKA CORPORATION (JP) 2014-09-18 US disclosed
US-8779015-B2 Method for recycling of phenolic antioxidant agent, process for production of olefin polymer, polyolefin powder, and fibers ADEKA CORPORATION (JP) 2014-07-15 US disclosed
US-20140001672-A1 POLYESTER RESIN COMPOSITION, POLYESTER FIBER, POLYESTER RESIN MOLDED ARTICLE, AND PROCESS FOR PRODUCTION OF NUCLEATING AGENT FOR POLYESTER RESIN ADEKA CORPORATION (JP) 2014-01-02 US disclosed
EP-2484725-A1 POLYESTER RESIN COMPOSITION, POLYESTER FIBER, POLYESTER RESIN MOLDED ARTICLE, AND PROCESS FOR PRODUCTION OF NUCLEATING AGENT FOR POLYESTER RESIN Adeka Corporation (JP) 2012-08-08 EP disclosed
US-20120189793-A1 POLYESTER RESIN COMPOSITION, POLYESTER FIBER, POLYESTER RESIN MOLDED ARTICLE, AND PROCESS FOR PRODUCTION OF NUCLEATING AGENT FOR POLYESTER RESIN ADEKA CORPORATION (JP) 2012-07-26 US disclosed
EP-2474561-A1 METHOD FOR RECYCLING OF PHENOLIC ANTIOXIDANT AGENT, PROCESS FOR PRODUCTION OF OLEFIN POLYMER, POLYOLEFIN POWDER, AND FIBERS Adeka Corporation (JP) 2012-07-11 EP disclosed
US-20120149838-A1 METHOD FOR RECYCLING OF PHENOLIC ANTIOXIDANT AGENT, PROCESS FOR PRODUCTION OF OLEFIN POLYMER, POLYOLEFIN POWDER, AND FIBERS ADEKA CORPORATION (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149838-A1 METHOD FOR RECYCLING OF PHENOLIC ANTIOXIDANT AGENT, PROCESS FOR PRODUCTION OF OLEFIN POLYMER, POLYOLEFIN POWDER, AND FIBERS GPX4, KEAP1, NOX4 NFE2L2 7/4885TFEB 1663/4885KDM4E 2778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.