Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | TPH1 | P17752 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19864372 | 0.85 | ATG4B (0.53) | CYP1A2ATG4BKDM1AMAOAMAOB | |
| SCHEMBL14714986 | 0.82 | NPSR1 (0.51) | CYP1A2ATG4BKDM1AMAOAMAOB | |
| SCHEMBL24487056 | 0.82 | ATG4B (0.51) | CYP1A2ATG4BKDM1AMAOAMAOB | |
| SCHEMBL21171722 | 0.82 | ATG4B (0.51) | CYP1A2ATG4BKDM1AMAOAMAOB | |
| SCHEMBL530807 | 0.80 | TRPM5 (0.50) | CYP1A2MGAMNPSR1HDAC6HDAC3 | |
| SCHEMBL529902 | 0.80 | MGAM (0.51) | CYP1A2MAOBMGAMNPSR1RAB9A | |
| SCHEMBL17909743 | 0.79 | RAB9A (0.62) | ATG4BHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL20247965 | 0.79 | ATG4B (0.48) | CYP1A2ATG4BKDM1AMAOAMAOB | |
| SCHEMBL28879876 | 0.79 | CYP1A2 (0.59) | CYP1A2ATG4BKDM1AMAOAMAOB | |
| SCHEMBL14714984 | 0.79 | KDM1A (0.48) | CYP1A2ATG4BKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040711-A2 | 2-OXO-1,2-DIHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND USES THEREOF AS ANTIPROLIFERATIVE AGENTS | Amphora Discovery Corporation (US) | 2009-04-01 | — | — | EP | claimed |
| WO-2007136592-A2 | 2-0X0-L,2-DIHYDR0QUIN0LINE DERIVATIVES, COMPOSITIONS, AND USES THEREOF AS ANTIPROLIFERATIVE AGENTS | AMPHORA DISCOVERY CORPORATION (US) | 2007-11-29 | — | — | WO | claimed |