Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | PYGL | P06737 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073094 | 0.94 | CHRM2 (0.49) | CHRM2CHRM4CHRM1PYGLALDH1A1 | |
| SCHEMBL4066758 | 0.93 | PYGL (0.50) | CHRM2CHRM4CHRM1PYGLALDH1A1 | |
| SCHEMBL4069399 | 0.87 | CHRM2 (0.48) | CHRM2CHRM4CHRM1PYGLALDH1A1 | |
| SCHEMBL4064769 | 0.86 | PYGL (0.49) | CHRM2CHRM4CHRM1PYGLALDH1A1 | |
| SCHEMBL4075040 | 0.85 | CHRM2 (0.54) | CHRM2CHRM4CHRM1ALDH1A1MAPT | |
| SCHEMBL4075144 | 0.85 | CHRM2 (0.51) | CHRM2CHRM4CHRM1ALDH1A1MAPT | |
| SCHEMBL4250746 | 0.82 | MEN1 (0.53) | CHRM2CHRM4CHRM1ALDH1A1MAPT | |
| SCHEMBL4066622 | 0.82 | CHRM2 (0.46) | CHRM2CHRM4CHRM1ALDH1A1MAPT | |
| SCHEMBL4073097 | 0.80 | CHRM2 (0.51) | CHRM2CHRM4CHRM1PYGLALDH1A1 | |
| SCHEMBL4066762 | 0.80 | PYGL (0.54) | CHRM2CHRM4CHRM1PYGLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |