Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075040 | 0.87 | CHRM2 (0.54) | ALDH1A1MAPTCHRM2CHRM4CHRM1 | |
| SCHEMBL4075144 | 0.87 | CHRM2 (0.51) | ALDH1A1MAPTCHRM2CHRM4CHRM1 | |
| SCHEMBL4069396 | 0.86 | CHRM2 (0.47) | PYGLACEALDH1A1MAPTCHRM2 | |
| SCHEMBL4066758 | 0.86 | PYGL (0.50) | PYGLACEALDH1A1MAPTCHRM2 | |
| SCHEMBL4064775 | 0.85 | PYGL (0.52) | PYGLACEALDH1A1CHRM2CHRM4 | |
| SCHEMBL4073094 | 0.85 | CHRM2 (0.49) | PYGLACEALDH1A1MAPTCHRM2 | |
| SCHEMBL4066622 | 0.84 | CHRM2 (0.46) | ALDH1A1MAPTCHRM2CHRM4CHRM1 | |
| SCHEMBL4250746 | 0.84 | MEN1 (0.53) | ALDH1A1MAPTCHRM2CHRM4CHRM1 | |
| SCHEMBL4072863 | 0.81 | L3MBTL1 (0.46) | PYGLACEALDH1A1MAPTCHRM2 | |
| SCHEMBL4064789 | 0.78 | POLB (0.47) | PYGLACEALDH1A1TSHRAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |