Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075040 | 0.98 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4066758 | 0.90 | PYGL (0.50) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4066622 | 0.90 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4250746 | 0.90 | MEN1 (0.53) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4073094 | 0.88 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4064769 | 0.87 | PYGL (0.49) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4069396 | 0.85 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4075145 | 0.85 | CHRM2 (0.53) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4072863 | 0.84 | L3MBTL1 (0.46) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4075043 | 0.82 | CHRM2 (0.56) | CHRM2CHRM4CHRM1CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PC, GOT2, PDK1 | CHRM2 2284/4885CHRM4 4269/4885CHRM1 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.