Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 3/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465734 | 0.93 | RORC (0.53) | RORCALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL1466192 | 0.83 | ALDH1A1 (0.60) | RORCALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL1464240 | 0.82 | CNR2 (0.48) | RORCCNR1CNR2ABCC9ABCC8 | |
| SCHEMBL1464950 | 0.82 | RORC (0.49) | RORCALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL1464685 | 0.80 | RORC (0.57) | RORCALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL1465949 | 0.79 | RORC (0.56) | RORCALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL12635982 | 0.79 | CNR2 (0.47) | RORCCNR1CNR2ABCC9ABCC8 | |
| SCHEMBL1465448 | 0.78 | ALDH1A1 (0.56) | RORCALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL1464507 | 0.76 | TAS2R14 (0.52) | RORCCNR1CNR2ABCC9ABCC8 | |
| SCHEMBL1465215 | 0.76 | CNR2 (0.46) | RORCCNR1CNR2ABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |