Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131039 | 0.88 | TSHR (0.42) | ALDH1A1ALOX15HPGDNAPRTPOLB | |
| SCHEMBL4191886 | 0.84 | ALDH1A1 (0.44) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4070091 | 0.81 | ALDH1A1 (0.56) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27763942 | 0.80 | KDM4E (0.49) | ALDH1A1ALOX15KDM4ENAPRTPTPN1 | |
| SCHEMBL27713874 | 0.80 | KMT2A (0.54) | ALDH1A1ALOX15KDM4ECA1CA2 | |
| SCHEMBL1227194 | 0.79 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL13587852 | 0.79 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3364459 | 0.79 | PTPN1 (0.45) | ALDH1A1ALOX15KDM4ESMN1; SMN2PTPN1 | |
| SCHEMBL10834328 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL14718826 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131527-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131527-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME | CLIC1, ASIC1, CLIC4 | ALDH1A1 1179/4885ALOX15 397/4885KDM4E 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.